Publications

Detailed Information

Ethanol-Dispersed Polymer Nanofibers as a Highly Selective Cell Isolation and Release Platform for CD4+ T Lymphocytes

DC Field Value Language
dc.contributor.authorJun, Seung-Hyun-
dc.contributor.authorKim, Kwanghee-
dc.contributor.authorAn, Hyo Jin-
dc.contributor.authorKim, Byoung Chan-
dc.contributor.authorSonn, Chung Hee-
dc.contributor.authorKim, Miju-
dc.contributor.authorDoh, Junsang-
dc.contributor.authorYee, Cassian-
dc.contributor.authorLee, Kyung-Mi-
dc.contributor.authorKim, Jungbae-
dc.date.accessioned2024-05-20T00:42:51Z-
dc.date.available2024-05-20T00:42:51Z-
dc.date.created2024-05-17-
dc.date.issued2012-11-
dc.identifier.citationAdvanced Functional Materials, Vol.22 No.21, pp.4448-4455-
dc.identifier.issn1616-301X-
dc.identifier.urihttps://hdl.handle.net/10371/203414-
dc.description.abstractA novel cell isolation and release platform using electrospun polystyrene-poly(styrene-co-maleic anhydride) (PS-PSMA) nanofibers is presented. Ethanol treatment of PS-PSMA nanofibers, employed for the purpose of sterilization, significantly increases their inter-fiber space for both antibody conjugation and subsequent cell separation. For the selective isolation of CD4(+) T cells from heterogeneous mixtures of mouse lymph nodes, capture efficiencies of up to 100% are achieved while maintaining cellular integrity and viability. Once captured, CD4(+) T lymphocytes can also be released from the NF scaffolds, further demonstrating its potential functionality as an immune cell-supporting and releasing matrix. This is the first demonstration of lymphocyte-culture scaffolds enabling selective isolation, accommodation, and sustained release of CD4(+) T cells for the purpose of cell therapies.-
dc.language영어-
dc.publisherJohn Wiley & Sons Ltd.-
dc.titleEthanol-Dispersed Polymer Nanofibers as a Highly Selective Cell Isolation and Release Platform for CD4+ T Lymphocytes-
dc.typeArticle-
dc.identifier.doi10.1002/adfm.201200657-
dc.citation.journaltitleAdvanced Functional Materials-
dc.identifier.wosid000310602700006-
dc.identifier.scopusid2-s2.0-84868537746-
dc.citation.endpage4455-
dc.citation.number21-
dc.citation.startpage4448-
dc.citation.volume22-
dc.description.isOpenAccessN-
dc.contributor.affiliatedAuthorDoh, Junsang-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.subject.keywordPlusPANCREATIC-CANCER-
dc.subject.keywordPlusPROTEIN-
dc.subject.keywordPlusELECTROSPUN-
dc.subject.keywordPlusDELIVERY-
dc.subject.keywordPlusCOATINGS-
dc.subject.keywordPlusHER2/NEU-
dc.subject.keywordAuthorelectrospun polymer nanofibers-
dc.subject.keywordAuthorethanol dispersion-
dc.subject.keywordAuthorCD4+T lymphocyte-
dc.subject.keywordAuthorcell separation-
dc.subject.keywordAuthorcell transplantation-
Appears in Collections:
Files in This Item:
There are no files associated with this item.

Related Researcher

  • College of Engineering
  • Department of Materials Science & Engineering
Research Area Ex Vivo Models, Lymphocyte Biology, Smart Biomaterials

Altmetrics

Item View & Download Count

  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Share