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Altered gene expression in cloned piglets

Cited 22 time in Web of Science Cited 26 time in Scopus
Authors

Tian, X. Cindy; Park, Joonghoon; Bruno, Richard; French, Richard; Jiang, Le; Prather, Randall S.

Issue Date
2009
Publisher
Commonwealth Scientific and Industrial Research Organization Publishing
Citation
Reproduction, Fertility and Development, Vol.21 No.1, pp.60-66
Abstract
Studies on cloned pigs are scant compared with those in mice and cattle. Expression profiles of cloned pig embryos on full-term cloned pigs are even more limited owing to the limited availability of DNA microarray technology in the pig. We have conducted expression profile comparisons between pigs from somatic cell nuclear transfer and pigs from conventional breeding at birth and 1 month of age. Differentially expressed genes that are subjected to DNA methylation were also examined for their DNA methylation status. These data will be presented in the 2009 Annual Meeting of the International Embryo Transfer Society in San Diego. In the present review, we focus on summarising existing findings on epigenetic and other changes in cloned embryo, cloned pigs and their offspring by conventional breeding.
ISSN
1031-3613
URI
https://hdl.handle.net/10371/203974
DOI
https://doi.org/10.1071/RD08214
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