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Admission hyperglycemia, stroke subtypes, outcomes in acute ischemic stroke
DC Field | Value | Language |
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dc.contributor.author | Kim, Joon-Tae | - |
dc.contributor.author | Lee, Ji Sung | - |
dc.contributor.author | Kim, Beom Joon | - |
dc.contributor.author | Kang, Jihoon | - |
dc.contributor.author | Lee, Keon-Joo | - |
dc.contributor.author | Park, Jong-Moo | - |
dc.contributor.author | Kang, Kyusik | - |
dc.contributor.author | Lee, Soo Joo | - |
dc.contributor.author | Kim, Jae Guk | - |
dc.contributor.author | Cha, Jae-Kwan | - |
dc.contributor.author | Kim, Dae-Hyun | - |
dc.contributor.author | Park, Tai Hwan | - |
dc.contributor.author | Lee, Kyung Bok | - |
dc.contributor.author | Lee, Jun | - |
dc.contributor.author | Hong, Keun-Sik | - |
dc.contributor.author | Cho, Yong-Jin | - |
dc.contributor.author | Park, Hong-Kyun | - |
dc.contributor.author | Lee, Byung-Chul | - |
dc.contributor.author | Yu, Kyung-Ho | - |
dc.contributor.author | Oh, Mi Sun | - |
dc.contributor.author | Kim, Dong-Eog | - |
dc.contributor.author | Choi, Jay Chol | - |
dc.contributor.author | Kwon, Jee-Hyun | - |
dc.contributor.author | Kim, Wook-Joo | - |
dc.contributor.author | Shin, Dong-Ick | - |
dc.contributor.author | Yum, Kyu Sun | - |
dc.contributor.author | Il Sohn, Sung | - |
dc.contributor.author | Hong, Jeong-Ho | - |
dc.contributor.author | Lee, Sang-Hwa | - |
dc.contributor.author | Park, Man-Seok | - |
dc.contributor.author | Choi, Kang-Ho | - |
dc.contributor.author | Ryu, Wi-Sun | - |
dc.contributor.author | Lee, Juneyoung | - |
dc.contributor.author | Saver, Jeffrey L. | - |
dc.contributor.author | Bae, Hee-Joon | - |
dc.date.accessioned | 2024-08-08T01:21:23Z | - |
dc.date.available | 2024-08-08T01:21:23Z | - |
dc.date.created | 2023-03-30 | - |
dc.date.created | 2023-03-30 | - |
dc.date.issued | 2023-02 | - |
dc.identifier.citation | Diabetes Research and Clinical Practice, Vol.196, p. 110257 | - |
dc.identifier.issn | 0168-8227 | - |
dc.identifier.uri | https://hdl.handle.net/10371/205341 | - |
dc.description.abstract | Aims: Whether admission hyperglycemia is differentially associated with early vascular outcomes in acute ischemic stroke (AIS) depending on stroke subtype has been incompletely delineated. Methods: In a multicenter, prospective stroke registry, patients with AIS were categorized based on admission glucose levels into normoglycemia, moderate hyperglycemia, and severe hyperglycemia (<140mg/dl, 140-179mg/dl, and >= 180mg/dl, respectively) groups. Multivariate analysis assessed the interaction between the hyperglycemia and ischemic stroke subtypes of large artery atherothrombosis (LAA), cardioembolism (CE), and small vessel occlusion (SVO) and early vascular outcomes (3-month stroke, all-cause mortality, and composite of stroke, MI, and all-cause mortality). Results: Among the 32,772 patients (age:69.0 +/- 12.6yrs, male:58.4%) meeting eligibility criteria, 61.9% were in the normoglycemia group, 19.5% were in the moderate hyperglycemia group, and 18.7% were in the severe hyperglycemia group. Substantial interactions between hyperglycemia groups and stroke subtypes were observed for 3-month stroke (Pinteraction = 0.003) and composite of stroke, MI, and all-cause mortality (Pinteraction = 0.001), with differential recurrence strongest among CE, intermediate among LAA, and least among SVO. Conclusions: Hyperglycemia was differently associated with the risk of 3-month stroke by ischemic stroke sub-type. The associations of hyperglycemia with 3-month stroke were greatest in CE subtype but not in SVO subtype. These results suggest that the effect of glucose-lowering treatment after AIS may differ according to stroke subtype. | - |
dc.language | 영어 | - |
dc.publisher | Elsevier BV | - |
dc.title | Admission hyperglycemia, stroke subtypes, outcomes in acute ischemic stroke | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.diabres.2023.110257 | - |
dc.citation.journaltitle | Diabetes Research and Clinical Practice | - |
dc.identifier.wosid | 000923488300001 | - |
dc.identifier.scopusid | 2-s2.0-85146599994 | - |
dc.citation.startpage | 110257 | - |
dc.citation.volume | 196 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Bae, Hee-Joon | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | POSTSTROKE HYPERGLYCEMIA | - |
dc.subject.keywordPlus | BLOOD-GLUCOSE | - |
dc.subject.keywordPlus | RISK-FACTOR | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | MULTICENTER | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordAuthor | Admission hyperglycemia | - |
dc.subject.keywordAuthor | Stroke subtype | - |
dc.subject.keywordAuthor | Acute ischemic stroke | - |
dc.subject.keywordAuthor | Early vascular outcome | - |
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