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Saccharobisindole, Neoasterric Methyl Ester, and 7-Chloro-4(1H)-quinolone: Three New Compounds Isolated from the Marine Bacterium Saccharomonospora sp.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Sohee | - |
dc.contributor.author | Le, Tu Cam | - |
dc.contributor.author | Han, Sang-Ah | - |
dc.contributor.author | Hillman, Prima F. | - |
dc.contributor.author | Hong, Ahreum | - |
dc.contributor.author | Hwang, Sunghoon | - |
dc.contributor.author | Du, Young Eun | - |
dc.contributor.author | Kim, Hiyoung | - |
dc.contributor.author | Oh, Dong-Chan | - |
dc.contributor.author | Cha, Sun-Shin | - |
dc.contributor.author | Lee, Jihye | - |
dc.contributor.author | Nam, Sang-Jip | - |
dc.contributor.author | Fenical, William | - |
dc.date.accessioned | 2024-08-08T01:22:54Z | - |
dc.date.available | 2024-08-08T01:22:54Z | - |
dc.date.created | 2022-02-10 | - |
dc.date.created | 2022-02-10 | - |
dc.date.issued | 2022-01 | - |
dc.identifier.citation | Marine Drugs, Vol.20 No.1, p. 35 | - |
dc.identifier.issn | 1660-3397 | - |
dc.identifier.uri | https://hdl.handle.net/10371/205546 | - |
dc.description.abstract | Analysis of the chemical components from the culture broth of the marine bacterium Saccharomonospora sp. CNQ-490 has yielded three novel compounds: saccharobisindole (1), neoasterric methyl ester (2), and 7-chloro-4(1H)-quinolone (3), in addition to acremonidine E (4), pinselin (5), penicitrinon A (6), and penicitrinon E (7). The chemical structures of the three novel compounds were elucidated by the interpretation of 1D, 2D nuclear magnetic resonance (NMR), and high-resolution mass spectrometry (HRMS) data. Compound 2 generated weak inhibition activity against Bacillus subtilis KCTC2441 and Staphylococcus aureus KCTC1927 at concentrations of 32 mu g/mL and 64 mu g/mL, respectively, whereas compounds 1 and 3 did not have any observable effects. In addition, compound 2 displayed weak anti-quorum sensing (QS) effects against S. aureus KCTC1927 and Micrococcus luteus SCO560. | - |
dc.language | 영어 | - |
dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | - |
dc.title | Saccharobisindole, Neoasterric Methyl Ester, and 7-Chloro-4(1H)-quinolone: Three New Compounds Isolated from the Marine Bacterium Saccharomonospora sp. | - |
dc.type | Article | - |
dc.identifier.doi | 10.3390/md20010035 | - |
dc.citation.journaltitle | Marine Drugs | - |
dc.identifier.wosid | 000747804000001 | - |
dc.identifier.scopusid | 2-s2.0-85121995406 | - |
dc.citation.number | 1 | - |
dc.citation.startpage | 35 | - |
dc.citation.volume | 20 | - |
dc.description.isOpenAccess | Y | - |
dc.contributor.affiliatedAuthor | Oh, Dong-Chan | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | XANTHONE DERIVATIVES | - |
dc.subject.keywordPlus | CITRININ DERIVATIVES | - |
dc.subject.keywordPlus | METABOLITES | - |
dc.subject.keywordPlus | ALKALOIDS | - |
dc.subject.keywordAuthor | Saccharomonospora sp | - |
dc.subject.keywordAuthor | marine natural products | - |
dc.subject.keywordAuthor | antibacterial activity | - |
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