Publications
Detailed Information
Association of Prediabetes and Type 2 Diabetes With Cognitive Function After Stroke: A STROKOG Collaboration Study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lo, Jessica W. | - |
dc.contributor.author | Crawford, John D. | - |
dc.contributor.author | Samaras, Katherine | - |
dc.contributor.author | Desmond, David W. | - |
dc.contributor.author | Kohler, Sebastian | - |
dc.contributor.author | Staals, Julie | - |
dc.contributor.author | Verhey, Frans R. J. | - |
dc.contributor.author | Bae, Hee-Joon | - |
dc.contributor.author | Lee, Keon-Joo | - |
dc.contributor.author | Kim, Beom Joon | - |
dc.contributor.author | Bordet, Regis | - |
dc.contributor.author | Cordonnier, Charlotte | - |
dc.contributor.author | Dondaine, Thibaut | - |
dc.contributor.author | Mendyk, Anne-Marie | - |
dc.contributor.author | Lee, Byung-Chul | - |
dc.contributor.author | Yu, Kyung-Ho | - |
dc.contributor.author | Lim, Jae-Sung | - |
dc.contributor.author | Kandiah, Nagaendran | - |
dc.contributor.author | Chander, Russell J. | - |
dc.contributor.author | Yatawara, Chathuri | - |
dc.contributor.author | Lipnicki, Darren M. | - |
dc.contributor.author | Sachdev, Perminder S. | - |
dc.date.accessioned | 2024-08-08T01:26:50Z | - |
dc.date.available | 2024-08-08T01:26:50Z | - |
dc.date.created | 2020-06-29 | - |
dc.date.created | 2020-06-29 | - |
dc.date.issued | 2020-06 | - |
dc.identifier.citation | Stroke, Vol.51 No.6, pp.1640-1646 | - |
dc.identifier.issn | 0039-2499 | - |
dc.identifier.uri | https://hdl.handle.net/10371/205982 | - |
dc.description.abstract | Background and Purpose- Type 2 diabetes mellitus (T2D) is associated with cognitive impairment and an increased risk of dementia, but the association between prediabetes and cognitive impairment is less clear, particularly in a setting of major cerebrovascular events. This article examines the impact of impaired fasting glucose and T2D on cognitive performance in a stroke population. Methods- Seven international observational studies from the STROKOG (Stroke and Cognition) consortium (n=1601; mean age, 66.0 years; 70% Asian, 26% white, and 2.6% African American) were included. Fasting glucose level (FGL) during hospitalization was used to define 3 groups, T2D (FGL >= 7.0 mmol/L), impaired fasting glucose (FGL 6.1-6.9 mmol/L), and normal (FGL <6.1 mmol/L), and a history of diabetes mellitus and the use of a diabetes mellitus medication were also used to support a diagnosis of T2D. Domain and global cognition Z scores were derived from standardized neuropsychological test scores. The cross-sectional association between glucose status and cognitive performance at 3 to 6 months poststroke was examined using linear mixed models, adjusting for age, sex, education, stroke type, ethnicity, and vascular risk factors. Results- Patients with T2D had significantly poorer performance in global cognition (SD, -0.59 [95% CI, -0.82 to -0.36]; P<0.001) and in all domains compared with patients with normal FGL. There was no significant difference between impaired fasting glucose patients and those with normal FGL in global cognition (SD, -0.10 [95% CI, -0.45 to 0.24]; P=0.55) or in any cognitive domain. Conclusions- Diabetes mellitus, but not prediabetes, is associated with poorer cognitive performance in patients 3 to 6 months after stroke. | - |
dc.language | 영어 | - |
dc.publisher | Lippincott Williams & Wilkins Ltd. | - |
dc.title | Association of Prediabetes and Type 2 Diabetes With Cognitive Function After Stroke: A STROKOG Collaboration Study | - |
dc.type | Article | - |
dc.identifier.doi | 10.1161/STROKEAHA.119.028428 | - |
dc.citation.journaltitle | Stroke | - |
dc.identifier.wosid | 000537785600011 | - |
dc.identifier.scopusid | 2-s2.0-85085537941 | - |
dc.citation.endpage | 1646 | - |
dc.citation.number | 6 | - |
dc.citation.startpage | 1640 | - |
dc.citation.volume | 51 | - |
dc.description.isOpenAccess | Y | - |
dc.contributor.affiliatedAuthor | Bae, Hee-Joon | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | IMPAIRED FASTING GLUCOSE | - |
dc.subject.keywordPlus | BLOOD-GLUCOSE | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | DECLINE | - |
dc.subject.keywordPlus | COMMUNITY | - |
dc.subject.keywordPlus | DEMENTIA | - |
dc.subject.keywordPlus | MELLITUS | - |
dc.subject.keywordAuthor | cognition | - |
dc.subject.keywordAuthor | diabetes mellitus | - |
dc.subject.keywordAuthor | prediabetic state | - |
dc.subject.keywordAuthor | stroke | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.