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Donghaesulfins A and B, dimeric benz[a]anthracene thioethers from volcanic island derived Streptomyces sp.

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dc.contributor.authorBae, Munhyung-
dc.contributor.authorAn, Joon Soo-
dc.contributor.authorBae, Eun Seo-
dc.contributor.authorOh, Jedo-
dc.contributor.authorPark, So Hyun-
dc.contributor.authorLim, Yeonjung-
dc.contributor.authorBan, Yeon Hee-
dc.contributor.authorKwon, Yun-
dc.contributor.authorCho, Jang-Cheon-
dc.contributor.authorYoon, Yeo Joon-
dc.contributor.authorLee, Sang Kook-
dc.contributor.authorShin, Jongheon-
dc.contributor.authorOh, Dong-Chan-
dc.date.accessioned2024-08-08T01:29:08Z-
dc.date.available2024-08-08T01:29:08Z-
dc.date.created2019-09-30-
dc.date.created2019-09-30-
dc.date.issued2019-05-
dc.identifier.citationOrganic Letters, Vol.21 No.10, pp.3635-3639-
dc.identifier.issn1523-7060-
dc.identifier.urihttps://hdl.handle.net/10371/206240-
dc.description.abstractThe chemical analysis of a Streptomyces strain, from a Korean volcanic island, discovered new benz[a]anthracene dimers linked by a thioether bond. The structures of donghaesulfins A and B (1 and 2) were elucidated by spectroscopic analysis including energy-dispersive X-ray. Their configurations were determined by ROESY NMR data, DP4 calculations, the modified Mosher's method, and ECD calculations. Donghaesulfins A (1) induced quinone reductase, whereas donghaesulfin B (2) displayed antiangiogenesis activity.-
dc.language영어-
dc.publisherAmerican Chemical Society-
dc.titleDonghaesulfins A and B, dimeric benz[a]anthracene thioethers from volcanic island derived Streptomyces sp.-
dc.typeArticle-
dc.identifier.doi10.1021/acs.orglett.9b01057-
dc.citation.journaltitleOrganic Letters-
dc.identifier.wosid000468696100035-
dc.identifier.scopusid2-s2.0-85065834190-
dc.citation.endpage3639-
dc.citation.number10-
dc.citation.startpage3635-
dc.citation.volume21-
dc.description.isOpenAccessN-
dc.contributor.affiliatedAuthorYoon, Yeo Joon-
dc.contributor.affiliatedAuthorLee, Sang Kook-
dc.contributor.affiliatedAuthorShin, Jongheon-
dc.contributor.affiliatedAuthorOh, Dong-Chan-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.subject.keywordPlusSULFUR-
dc.subject.keywordPlusOHMYUNGSAMYCINS-
dc.subject.keywordPlusANTIBIOTICS-
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  • College of Pharmacy
  • Department of Manufacturing Pharmacy
Research Area Chemical biology of natural products, Drug discovery from microbial natural products, Study of insect-microbial symbiosis, 미생물 유래 생리활성 천연물 발굴, 천연물 구조 분석

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