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Dose-Dependent Effect of Statin Pretreatment on Preventing the Periprocedural Complications of Carotid Artery Stenting
DC Field | Value | Language |
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dc.contributor.author | Hong, Jeong-Ho | - |
dc.contributor.author | Sohn, Sung-Il | - |
dc.contributor.author | Kwak, Jaehyuk | - |
dc.contributor.author | Yoo, Joonsang | - |
dc.contributor.author | Chang, Hyuk Won | - |
dc.contributor.author | Kwon, O-Ki | - |
dc.contributor.author | Jung, Cheolkyu | - |
dc.contributor.author | Chung, Inyoung | - |
dc.contributor.author | Bae, Hee-Joon | - |
dc.contributor.author | Lee, Ji Sung | - |
dc.contributor.author | Han, Moon-Ku | - |
dc.date.accessioned | 2024-08-08T01:33:44Z | - |
dc.date.available | 2024-08-08T01:33:44Z | - |
dc.date.created | 2018-08-29 | - |
dc.date.created | 2018-08-29 | - |
dc.date.issued | 2017-07 | - |
dc.identifier.citation | Stroke, Vol.48 No.7, pp.1890-1894 | - |
dc.identifier.issn | 0039-2499 | - |
dc.identifier.uri | https://hdl.handle.net/10371/206687 | - |
dc.description.abstract | Background and Purpose-We investigated whether statin pretreatment can dose dependently reduce periprocedural complications in patients undergoing carotid artery stenting because of symptomatic carotid artery stenosis. Methods-We enrolled a consecutive series of 397 symptomatic carotid artery stenosis (>= 50% stenosis on conventional angiography) treated with carotid artery stenting at 2 tertiary university hospitals over a decade. Definition of periprocedural complications included any stroke, myocardial infarction, and death within 1 month after or during the procedure. Statin pretreatment was divided into 3 categories according to the atorvastatin equivalent dose: none (n=158; 39.8%), standard dose (<40 mg of atorvastatin, n=155; 39.0%), and high dose (>= 40 mg; n=84; 21.2%). A multivariable logistic regression analysis with the generalized estimating equation method was used to investigate independent factors in periprocedural complications. Results-The patients' mean age was 68.7 years (81.6% men). The periprocedural complication rates across the 3 categories of statin use were 12.0%, 4.5%, and 1.2%. After adjustment, a change in the atorvastatin dose category was associated with reduction in the odds of periprocedural complications for each change in dose category (standard-dose statin: odds ratio, 0.24; 95% confidence interval, 0.07-0.81; high-dose statin: odds ratio, 0.11; 95% confidence interval, 0.01-0.96; P for trend=0.01). Administration of antiplatelet drugs was also an independent factor in periprocedural complications (OR, 0.18; 95% CI, 0.05-0.69). Conclusions-This study shows that statin pretreatment may reduce the incidence of periprocedural complications dose dependently in patients with symptomatic carotid artery stenting. | - |
dc.language | 영어 | - |
dc.publisher | Lippincott Williams & Wilkins Ltd. | - |
dc.title | Dose-Dependent Effect of Statin Pretreatment on Preventing the Periprocedural Complications of Carotid Artery Stenting | - |
dc.type | Article | - |
dc.identifier.doi | 10.1161/STROKEAHA.117.016680 | - |
dc.citation.journaltitle | Stroke | - |
dc.identifier.wosid | 000404044100046 | - |
dc.identifier.scopusid | 2-s2.0-85021075898 | - |
dc.citation.endpage | 1894 | - |
dc.citation.number | 7 | - |
dc.citation.startpage | 1890 | - |
dc.citation.volume | 48 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Kwon, O-Ki | - |
dc.contributor.affiliatedAuthor | Bae, Hee-Joon | - |
dc.contributor.affiliatedAuthor | Han, Moon-Ku | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | STROKE PREVENTION | - |
dc.subject.keywordPlus | CORONARY INTERVENTION | - |
dc.subject.keywordPlus | MYOCARDIAL-INFARCTION | - |
dc.subject.keywordPlus | AGGRESSIVE REDUCTION | - |
dc.subject.keywordPlus | CHOLESTEROL LEVELS | - |
dc.subject.keywordPlus | ISCHEMIC-STROKE | - |
dc.subject.keywordPlus | ATORVASTATIN | - |
dc.subject.keywordPlus | ENDARTERECTOMY | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | ANGIOPLASTY | - |
dc.subject.keywordAuthor | cerebral infarction | - |
dc.subject.keywordAuthor | carotid stenosis | - |
dc.subject.keywordAuthor | cerebrovascular disorders | - |
dc.subject.keywordAuthor | hydroxymethylglutaryl-CoA reductase inhibitors | - |
dc.subject.keywordAuthor | stroke | - |
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