Publications

Detailed Information

A methodological perspective on the longitudinal cognitive change after stroke

DC Field Value Language
dc.contributor.authorLim, Jae-Sung-
dc.contributor.authorNoh, Maengseok-
dc.contributor.authorKim, Beom Joon-
dc.contributor.authorHan, Moon-Ku-
dc.contributor.authorKim, Sangyun-
dc.contributor.authorJang, Myung Suk-
dc.contributor.authorLee, Youngjo-
dc.contributor.authorHa, Il Do-
dc.contributor.authorYu, Kyung-Ho-
dc.contributor.authorLee, Byung-Chul-
dc.contributor.authorKang, Yeonwook-
dc.contributor.authorLee, Juneyoung-
dc.contributor.authorBae, Hee-Joon-
dc.date.accessioned2024-08-08T01:33:58Z-
dc.date.available2024-08-08T01:33:58Z-
dc.date.created2018-11-07-
dc.date.created2018-11-07-
dc.date.issued2017-04-
dc.identifier.citationDementia and Geriatric Cognitive Disorders, Vol.44 No.5-6, pp.311-319-
dc.identifier.issn1420-8008-
dc.identifier.urihttps://hdl.handle.net/10371/206726-
dc.description.abstractBackground/Aims: Most studies of poststroke cognitive impairment (PSCI) have analyzed cognitive levels at specific time points rather than their changes over time. Furthermore, they seldom consider correlations between cognitive domains. We aimed to investigate the effects of these methodological considerations on determining significant PSCI predictors in a longitudinal stroke cohort. Methods: In patients who underwent neuropsychological tests at least twice after stroke, we adopted a multilevel hierarchical mixed-effects model with domain-specific cognitive changes and a multivariate model for multiple outcomes to reflect their correlations. Results: We enrolled 375 patients (median follow-up of 34.1 months). Known predictors of PSCI were generally associated with cognitive levels; however, most of the statistical significances disappeared when cognitive changes were set as outcomes, except age for memory, prior stroke and baseline cognition for executive/attention domain, and baseline cognition for visuospatial function. The multivariate analysis which considered multiple outcomes simultaneously further altered these associations. Conclusions: This study shows that defining outcomes as changes over time and reflecting correlations between outcomes may affect the identification of predictors of PSCI. © 2018 S. Karger AG, Basel-
dc.language영어-
dc.publisherS. Karger AG-
dc.titleA methodological perspective on the longitudinal cognitive change after stroke-
dc.typeArticle-
dc.identifier.doi10.1159/000484477-
dc.citation.journaltitleDementia and Geriatric Cognitive Disorders-
dc.identifier.wosid000425254900007-
dc.identifier.scopusid2-s2.0-85041599169-
dc.citation.endpage319-
dc.citation.number5-6-
dc.citation.startpage311-
dc.citation.volume44-
dc.description.isOpenAccessN-
dc.contributor.affiliatedAuthorBae, Hee-Joon-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.subject.keywordPlusIMPAIRMENT HARMONIZATION STANDARDS-
dc.subject.keywordPlusDEMENTIA-
dc.subject.keywordPlusPROGRESSION-
dc.subject.keywordPlusDECLINE-
dc.subject.keywordPlusKOREA-
dc.subject.keywordPlusLOBES-
dc.subject.keywordAuthorPoststroke cognitive impairment-
dc.subject.keywordAuthorVascular cognitive impairment-
dc.subject.keywordAuthorVascular causes of cognitive impairment-
dc.subject.keywordAuthorMultivariate analysis-
dc.subject.keywordAuthorMixed model-
dc.subject.keywordAuthorLongitudinal study-
Appears in Collections:
Files in This Item:
There are no files associated with this item.

Related Researcher

  • College of Medicine
  • Department of Medicine
Research Area 뇌경색, 뇌졸중, 혈관성 인지장애 및 치매

Altmetrics

Item View & Download Count

  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Share