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A low-salt diet increases the estimated net endogenous acid production in nondiabetic chronic kidney disease patients treated with angiotensin receptor blockade
DC Field | Value | Language |
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dc.contributor.author | Baek, Seon Ha | - |
dc.contributor.author | Kim, Sejoong | - |
dc.contributor.author | Kim, Dong Ki | - |
dc.contributor.author | Park, Jung Hwan | - |
dc.contributor.author | Shin, Sung Joon | - |
dc.contributor.author | Lee, Sang Ho | - |
dc.contributor.author | Choi, Bum Soon | - |
dc.contributor.author | Chin, Ho Jun | - |
dc.contributor.author | Kim, Suhnggwon | - |
dc.contributor.author | Lim, Chun Soo | - |
dc.date.accessioned | 2024-08-08T01:41:01Z | - |
dc.date.available | 2024-08-08T01:41:01Z | - |
dc.date.created | 2018-12-14 | - |
dc.date.created | 2018-12-14 | - |
dc.date.issued | 2015-01 | - |
dc.identifier.citation | Nephron - Clinical Practice, Vol.128 No.3-4, pp.407-413 | - |
dc.identifier.issn | 1660-2110 | - |
dc.identifier.uri | https://hdl.handle.net/10371/207299 | - |
dc.description.abstract | Background/Aims: An acid-base imbalance precedes renal disease progression in patients with chronic kidney disease (CKD). Little is known about the effects of a low-salt diet (LSD) on net endogenous acid production (NEAP) levels in CKD patients using angiotensin receptor blockade. Methods: We enrolled a total of 202 nondiabetic CKD patients who underwent an 8-week treatment with olmesartan from the original trial [Effects of Low Sodium Intake on the Anti-proteinuric Efficacy of Olmesartan in Hypertensive Patients with Albuminuria (ESPECIAL) trial: NCT01552954]. The patients were divided into good-and poor-LSD-compliance groups. Results: During the interventional 8 weeks, the NEAP in the good-compliance group increased compared to the control group (12.9 +/- 32.0 vs. -2.0 +/- 35.0 mmol/day, p = 0.002). NEAP was positively associated with the good-LSD-compliance group in the fully adjusted analyses (r = 0.135, p = 0.016). The additional reduction of 2.39 g/day of protein intake with a reduction of 1 g/day of salt intake did not increase the NEAP under angiotensin II receptor blockade (ARB) treatment with an LSD (r = 0.546, p < 0.001). Conclusion: We found that an LSD may increase the NEAP in nondiabetic CKD patients using ARB, which suggests that additional acid producing-protein restriction should be required to prevent the NEAP from rising. (C) 2014 S. Karger AG, Basel | - |
dc.language | 영어 | - |
dc.publisher | S. Karger AG | - |
dc.title | A low-salt diet increases the estimated net endogenous acid production in nondiabetic chronic kidney disease patients treated with angiotensin receptor blockade | - |
dc.type | Article | - |
dc.identifier.doi | 10.1159/000369558 | - |
dc.citation.journaltitle | Nephron - Clinical Practice | - |
dc.identifier.wosid | 000349411500031 | - |
dc.identifier.scopusid | 2-s2.0-84922867818 | - |
dc.citation.endpage | 413 | - |
dc.citation.number | 3-4 | - |
dc.citation.startpage | 407 | - |
dc.citation.volume | 128 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Kim, Dong Ki | - |
dc.contributor.affiliatedAuthor | Lim, Chun Soo | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | METABOLIC-ACIDOSIS | - |
dc.subject.keywordPlus | SERUM BICARBONATE | - |
dc.subject.keywordPlus | BLOOD-PRESSURE | - |
dc.subject.keywordPlus | POTASSIUM | - |
dc.subject.keywordPlus | PROGRESSION | - |
dc.subject.keywordPlus | REDUCTION | - |
dc.subject.keywordPlus | NITROGEN | - |
dc.subject.keywordPlus | HUMANS | - |
dc.subject.keywordPlus | GFR | - |
dc.subject.keywordAuthor | Low-salt diet | - |
dc.subject.keywordAuthor | Acidosis | - |
dc.subject.keywordAuthor | Angiotensin receptor blockade | - |
dc.subject.keywordAuthor | Chronic kidney disease | - |
dc.subject.keywordAuthor | Nutrition | - |
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