안면부의 조직공학적 재생을 위한 발생영역 수복에 대한 고찰

Abstract

In growing child, corrective surgery for congenital malformation can cause complication and problems, such as repetitive relapse and growth disturbance over time. These are because the biologic rationale of the procedure is incorrect, and the anatomic pattern of relapse points an accusatory finger at the pathology. Recent updates in surgical approach for the clefting are focused on facial development and origin of clefting. Successful treatment of congenital craniofacial defect can be acquired by understanding of developmental processes. The developmental field repair (DFR) is based on the neuromeric model, which propose facial tissues are originated from embryonic nervous system. This concept consider the identification and reassignment specific developemental field. Goals of DFR surgery are 1) resolution of all pathologic processes of clefting, 2) dissection following the embryonic separation plane, 3) preservation of vascular supply for alveolar mucoperiosteum, 4) primary unification of alveolus, 5) reassignment of all developmental field to correct relation. Therefore, understanding of developmental field theory must be proceeded surgical approach. This concepts are based on reconstruction of deformed tissues following embryonic origin, which are able to be functional and anatomical repair. Therefore, in this article the author reviewed the developmental neuromeric theory, and the developmental field repair concept based on this neuromeric model.