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Dehydrothermal Treatment로 제작한 흡수성 콜라겐 골유도재생술 차단막 : Absorbable Guided Bone Regeneration Membrane Fabricated from Dehydrothermal Treated Porcine Collagen
DC Field | Value | Language |
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dc.contributor.author | 방강미 | - |
dc.contributor.author | 정한울 | - |
dc.contributor.author | 김성포 | - |
dc.contributor.author | 양은경 | - |
dc.contributor.author | 김기호 | - |
dc.contributor.author | 김성민 | - |
dc.contributor.author | 김명진 | - |
dc.contributor.author | 장정원 | - |
dc.contributor.author | 이종호 | - |
dc.date.accessioned | 2024-08-08T01:46:23Z | - |
dc.date.available | 2024-08-08T01:46:23Z | - |
dc.date.created | 2020-07-03 | - |
dc.date.created | 2020-07-03 | - |
dc.date.issued | 2011-03 | - |
dc.identifier.citation | Maxillofacial Plastic and Reconstructive Surgery, Vol.33 No.2, pp.112-119 | - |
dc.identifier.issn | 2288-8101 | - |
dc.identifier.uri | https://hdl.handle.net/10371/208014 | - |
dc.description.abstract | Purpose: Collagen membranes are used extensively as bioabsorbable barriers in guided bone regeneration. However, collagen has different effects on tissue restoration depending on the type, structure, degree of cross-linking and chemical treatment. The purpose of this study was to evaluate the inflammatory reaction, bone formation, and degradation of dehydrothermal treated porcine type I atelocollagen (CollaGuide?) compared to of the non-crosslinked porcine type I, III collagen (BioGide?) and the glutaldehyde cross-linked bovine type I collagen (BioMend?) in surgically created bone defects in rat mandible. Methods: Bone defect model was based upon 3 mm sized full-thickness transcortical bone defects in the mandibular ramus of Sprague-Dawley rats. The defects were covered bucolingually with CollaGuide?, BioMend?, or BioGide? (n=12). For control, the defects were not covered by any membrane. Lymphocyte, multinucleated giant cell infiltration, bone formation over the defect area and membrane absorption were evaluated at 4 weeks postimplantation. For comparison of the membrane effect over the bone augmentation, rats received a bone graft plus different covering of membrane. A 3×4 mm sized block graft was harvested from the mandibular angle and was laid and stabilized with a microscrew on the naturally existing curvature of mandibular inferior border. After 10 weeks postimplantation, same histologic analysis were done. 원고접수일 2010년 9월 20일, 게재확정일 2011년 1월 4일책임저자 이종호(110-749) 서울시 종로구 연건동 28번지, 서울대학교 치의학대학원 구강악안면외과학교실Tel: 02-2072-2630, Fax: 02-766-4948, E-mail: leejongh@snu.ac.kr RECEIVED September 20, 2010, ACCEPTED January 4, 2011Correspondence to Jong-Ho Lee Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University 28, Yeongun-dong, Chongro-gu, Seoul 110-749, Korea Tel: 82-2-2072-2630, Fax: 82-2-766-4948, E-mail: leejongh@snu.ac.kr CC This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Results: In the defect model at 4 weeks post-implantation, the amount of new bone formed in defects was similar for all types of membrane. Bio-Gide? membranes induced significantly greater inflammatory response and membrane resorption than other two membranes; characterized by lymphocytes and multinucleated giant cells. At 10 weeks postoperatively, all membranes were completely resorbed. Conclusion: Dehydrotheramal treated cross-linked collagen was safe and effective in guiding bone regeneration in alveolar ridge defects and bone augmentation in rats, similar to BioGide? and BioMend?, thus, could be clinically useful. | - |
dc.language | 한국어 | - |
dc.publisher | 대한악안면성형재건외과학회 | - |
dc.title | Dehydrothermal Treatment로 제작한 흡수성 콜라겐 골유도재생술 차단막 | - |
dc.title.alternative | Absorbable Guided Bone Regeneration Membrane Fabricated from Dehydrothermal Treated Porcine Collagen | - |
dc.type | Article | - |
dc.citation.journaltitle | Maxillofacial Plastic and Reconstructive Surgery | - |
dc.citation.endpage | 119 | - |
dc.citation.number | 2 | - |
dc.citation.startpage | 112 | - |
dc.citation.volume | 33 | - |
dc.identifier.kciid | ART001542094 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | 김성민 | - |
dc.contributor.affiliatedAuthor | 김명진 | - |
dc.contributor.affiliatedAuthor | 이종호 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 2 | - |
dc.subject.keywordAuthor | Guided bone regeneration, Type I collagen, Dehydrothermal treatment | - |
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