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Sceliphrolactam, a polyene macrocyclic lactam from a wasp-associated Streptomyces sp.
Cited 88 time in
Web of Science
Cited 98 time in Scopus
- Authors
- Issue Date
- 2011-02
- Publisher
- American Chemical Society
- Citation
- Organic Letters, Vol.13 No.4, pp.752-755
- Abstract
- A previously unreported 26-membered polyene macrocyclic lactam, sceliphrolactam, was Isolated from an actinomycete, Streptomyces sp., associated with the mud dauber, Sceliphron caementarium. Sceliphrolactam's structure was determined by 1D- and 2D-NMR, MS, UV, and IR spectral analysis. Sceliphrolactam displays antifungal activity against amphotericin B-resistant Candida albicans (MIC = 4 mu g/mL, 8.3 mu M).
- ISSN
- 1523-7060
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Related Researcher
- College of Pharmacy
- Department of Manufacturing Pharmacy
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