Publications
Detailed Information
Traditional herbal medicines, Fuling, Baizhu, and Danggui, promote the proliferation of human Schwann cells
Cited 1 time in
Web of Science
Cited 2 time in Scopus
- Authors
- Issue Date
- 2010-08
- Publisher
- Neural Regeneration Research
- Citation
- Neural Regeneration Research, Vol.5 No.16, pp.1216-1219
- Abstract
- Enhancing Schwann cell proliferation may be beneficial for peripheral nerve repair and nerve regeneration. A traditional herbal formula composed of Fuling (poria cocos), Baizhu (Atractylodes macrocephala), and Danggui (Angelica sinensis) (FBD) improves neuronal survival and growth, and FBD may promote the secretion of brain-derived neurotrophic factor. However, the mechanism underlying Schwann cell proliferation remains unclear. We tested whether FBD enhanced the proliferation of human Schwann cells. FBD (20 mu g/mL) increased Schwann cell viability and survival, and increased the number of cells at G2/M and S phases. FBD also increased nerve growth factor and brain-derived neurotrophic factor expression in Schwann cells, with maximum efficacy at 20 mu g/mL.
- ISSN
- 1673-5374
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.