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Predictors of persistent airway stenosis in patients with endobronchial tuberculosis
DC Field | Value | Language |
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dc.contributor.author | Um, S. -W. | - |
dc.contributor.author | Yoon, Y. S. | - |
dc.contributor.author | Lee, S. -M. | - |
dc.contributor.author | Yim, J. -J. | - |
dc.contributor.author | Yoo, C. -G. | - |
dc.contributor.author | Chung, H. S. | - |
dc.contributor.author | Kim, Y. W. | - |
dc.contributor.author | Han, S. K. | - |
dc.contributor.author | Shim, Y. -S. | - |
dc.contributor.author | Kim, D. K. | - |
dc.date.accessioned | 2024-08-08T01:49:17Z | - |
dc.date.available | 2024-08-08T01:49:17Z | - |
dc.date.created | 2023-07-25 | - |
dc.date.created | 2023-07-25 | - |
dc.date.issued | 2008-01 | - |
dc.identifier.citation | International Journal of Tuberculosis and Lung Disease, Vol.12 No.1, pp.57-62 | - |
dc.identifier.issn | 1027-3719 | - |
dc.identifier.uri | https://hdl.handle.net/10371/208409 | - |
dc.description.abstract | SETTING: The university and municipal hospitals in Seoul, Korea. OBJECTIVE: To evaluate the predictors of persistent airway stenosis following anti-tuberculosis chemotherapy in patients with endobronchial tuberculosis (TB). DESIGN: Diagnosis of TB was confirmed by microbiology or histopathology. Bronchoscopic examinations revealed that patients had endobronchial lesions compatible with endobronchial TB. Study subjects had at least one follow-up bronchoscopy to evaluate their treatment response. Treatment response was determined by changes in the degree or extent of airway stenosis between the first and last bronchoscopic examinations. RESULTS: Sixty-seven subjects were recruited retrospectively from Seoul National University Hospital and Seoul National University Boramae Hospital. Persistent bronchostenosis occurred in 41.8% of the patients. In multivariate regression analysis, age >45 years (OR 3.65), pure or combined fibrostenotic subtype (OR 5.54) and duration from onset of chief complaint to the initiation of anti-tuberculosis chemotherapy >90 days (OR 5.98) were identified as independent predictors of persistent airway stenosis. Oral corticosteroids (prednisolone equivalent >= 30 mg/d) did not reduce the frequency of persistent airway stenosis. CONCLUSION: Early diagnosis and early administration of anti-tuberculosis chemotherapy before involvement of the deeper airways is important to prevent the development of unwanted sequelae of bronchostenosis. | - |
dc.language | 영어 | - |
dc.publisher | International Union Against Tuberculosis And Lung Disease/Union Internationale Contre la Tuberculose et les Maladies Respiratories | - |
dc.title | Predictors of persistent airway stenosis in patients with endobronchial tuberculosis | - |
dc.type | Article | - |
dc.citation.journaltitle | International Journal of Tuberculosis and Lung Disease | - |
dc.identifier.wosid | 000251868600012 | - |
dc.identifier.scopusid | 2-s2.0-38349041743 | - |
dc.citation.endpage | 62 | - |
dc.citation.number | 1 | - |
dc.citation.startpage | 57 | - |
dc.citation.volume | 12 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Lee, S. -M. | - |
dc.contributor.affiliatedAuthor | Yim, J. -J. | - |
dc.contributor.affiliatedAuthor | Yoo, C. -G. | - |
dc.contributor.affiliatedAuthor | Chung, H. S. | - |
dc.contributor.affiliatedAuthor | Kim, Y. W. | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | FIBEROPTIC BRONCHOSCOPY | - |
dc.subject.keywordPlus | DIAGNOSTIC FEATURES | - |
dc.subject.keywordPlus | CHEMOTHERAPY | - |
dc.subject.keywordAuthor | bronchoscopy | - |
dc.subject.keywordAuthor | bronchostenosis | - |
dc.subject.keywordAuthor | corticosteroids | - |
dc.subject.keywordAuthor | tuberculosis | - |
dc.subject.keywordAuthor | tuberculous tracheobronchitis | - |
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