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Induction of telomerase activity during an early burst of proliferation in pancreatic regeneration
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Oh, Bong Kyeong | - |
dc.contributor.author | Seong, Je Kyung | - |
dc.contributor.author | Lee, Jeung Eun | - |
dc.contributor.author | Chae, Kwang Jo | - |
dc.contributor.author | Roh, Kyung Jin | - |
dc.contributor.author | Park, Chanil | - |
dc.contributor.author | Park, Young Nyun | - |
dc.date.accessioned | 2024-08-08T01:51:23Z | - |
dc.date.available | 2024-08-08T01:51:23Z | - |
dc.date.created | 2022-05-09 | - |
dc.date.created | 2022-05-09 | - |
dc.date.issued | 2002-12 | - |
dc.identifier.citation | Cancer Letters, Vol.186 No.1, pp.93-98 | - |
dc.identifier.issn | 0304-3835 | - |
dc.identifier.uri | https://hdl.handle.net/10371/208716 | - |
dc.description.abstract | Telomerase activity (TA) and telomerase reverse transcriptase (rTERT) were investigated in Sprague-Dawley rats, killed at 6 and 12 h, and 1, 2, 3, 7, and 14 days after 90% pancreatectomy (px), by TRAPeze enzyme-linked immunosorbent assay telomerase detection and reverse transcriptase-polymerase chain reaction. TA increased at 2 days and reached a maximum at 3 days after px, when the small ductules showed the highest proliferation activity. After 3 days, TA decreased to basal levels as the ductules differentiated into new endocrine and exocrine pancreas. The expression of rTERT showed a correlation with TA. These results suggest telomerase is actively regulated during pancreatic regeneration. (C) 2002 Elsevier Science Ireland Ltd. All ri-hts reserved. | - |
dc.language | 영어 | - |
dc.publisher | Elsevier BV | - |
dc.title | Induction of telomerase activity during an early burst of proliferation in pancreatic regeneration | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/S0304-3835(02)00320-8 | - |
dc.citation.journaltitle | Cancer Letters | - |
dc.identifier.wosid | 000179253100012 | - |
dc.identifier.scopusid | 2-s2.0-0036883594 | - |
dc.citation.endpage | 98 | - |
dc.citation.number | 1 | - |
dc.citation.startpage | 93 | - |
dc.citation.volume | 186 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Seong, Je Kyung | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | CELL-LINES | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | DIFFERENTIATION | - |
dc.subject.keywordPlus | RAT | - |
dc.subject.keywordPlus | EPITHELIUM | - |
dc.subject.keywordPlus | EXOCRINE | - |
dc.subject.keywordPlus | ACINAR | - |
dc.subject.keywordPlus | GROWTH | - |
dc.subject.keywordAuthor | pancreas | - |
dc.subject.keywordAuthor | regeneration | - |
dc.subject.keywordAuthor | telomerase | - |
dc.subject.keywordAuthor | telomerase reverse transcriptase | - |
dc.subject.keywordAuthor | proliferation | - |
dc.subject.keywordAuthor | pancreatectomy | - |
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