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A spindle cell tumor of unknown origin and diffuse bone marrow involvement in a patient with hypercalcemia
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yim, JJ | - |
dc.contributor.author | Kang, GH | - |
dc.contributor.author | Heo, DS | - |
dc.contributor.author | Kim, NK | - |
dc.date.accessioned | 2024-08-08T01:51:54Z | - |
dc.date.available | 2024-08-08T01:51:54Z | - |
dc.date.created | 2023-07-25 | - |
dc.date.created | 2023-07-25 | - |
dc.date.issued | 1999-11 | - |
dc.identifier.citation | Tumori, Vol.85 No.6, pp.526-529 | - |
dc.identifier.issn | 0300-8916 | - |
dc.identifier.uri | https://hdl.handle.net/10371/208796 | - |
dc.description.abstract | Background: Metastasis of unknown origin in bone marrow is infrequent, although, when it occurs, adenocarcinoma is the most common histologic type. Involvement of bone marrow by a spindle cell tumor and presentation with hypercalcemia are very rare. Method: This report describes a 21-year-old man with diffuse bone marrow involvement from a spindle cell tumor. Results: The patient presented with low back pain, anemia, thrombocytopenia, azotemia, and hypercalcemia. Bone marrow biopsy revealed a spindle cell tumor that was positive for vimentin staining but whose primary site could not be identified. A bone marrow scan revealed absence of uptake, which suggested systemic disease. We treated this case as a type of sarcoma by giving combined chemotherapy consisting of vincristine, actinomycin-D and cyclophosphamide, The patient showed a clinical response for seven months, but the disease progressed despite chemotherapy and he died one year after diagnosis. Conclusions: We have documented a rare case of spindle cell tumor involving bone marrow without evidence of the tumor's primary site. | - |
dc.language | 영어 | - |
dc.publisher | II Pensiero Scientifico Editore srl | - |
dc.title | A spindle cell tumor of unknown origin and diffuse bone marrow involvement in a patient with hypercalcemia | - |
dc.type | Article | - |
dc.identifier.doi | 10.1177/030089169908500621 | - |
dc.citation.journaltitle | Tumori | - |
dc.identifier.wosid | 000085717800021 | - |
dc.identifier.scopusid | 2-s2.0-0342514675 | - |
dc.citation.endpage | 529 | - |
dc.citation.number | 6 | - |
dc.citation.startpage | 526 | - |
dc.citation.volume | 85 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Yim, JJ | - |
dc.contributor.affiliatedAuthor | Heo, DS | - |
dc.contributor.affiliatedAuthor | Kim, NK | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordAuthor | metastasis of unknown origin | - |
dc.subject.keywordAuthor | spindle cell tumor | - |
dc.subject.keywordAuthor | hypercalcemia | - |
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