S-Space College of Medicine/School of Medicine (의과대학/대학원) Neuroscience (뇌신경과학전공) Journal Papers (저널논문_뇌신경과학전공)
Renal tissue reconstitution by the implantation of renal segments on biodegradable polymer scaffolds
- Issue Date
- Springer Verlag
- Biotechnol Lett. 2003 Sep;25(18):1505-8.
- Animals ; Animals, Newborn ; Cell Division/physiology ; Culture Techniques/*methods ; Extracellular Matrix/physiology ; Graft Survival/*physiology ; Kidney/*cytology/*growth & development/surgery ; Kidney Transplantation/*methods ; Membranes, Artificial ; Polyglycolic Acid ; Rats ; Rats, Sprague-Dawley ; Regeneration/*physiology ; Tissue Engineering/*methods ; Absorbable Implants
- Renal units were created in vivo by transplanting isolated renal segments on three-dimensional, biodegradable polymer scaffolds. Renal segments, freshly isolated from rat kidneys, were seeded on polymer scaffolds and subcutaneously implanted in athymic mice for two and four weeks. Three-dimensional renal reconstructs were formed with glomeruli and tubules, showing a possibility of reconstituting renal structures by transplanting renal segments.
- 0141-5492 (Print)
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