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Comparison of Delta FVC (% decrease in FVC at the PC(20)) between cough-variant asthma and classic asthma

Cited 9 time in Web of Science Cited 11 time in Scopus
Authors
Yoo, Young; Yu, Jinho; Lee, Sun Hee; Kim, Do Kyun; Choi, Sun Hee; Kim, Chang Keun; Koh, Young Yull
Issue Date
2007-03-17
Publisher
Taylor & Francis
Citation
J Asthma. 2007 Jan-Feb;44(1):35-8.
Keywords
Asthma/*classification/*physiopathologyBronchial Provocation TestsBronchoconstrictor Agents/diagnostic useChildCough/*classification/*physiopathologyFemaleHumansMaleMethacholine Chloride/diagnostic useRetrospective StudiesVital Capacity
Abstract
The percentage decrease in forced vital capacity (FVC) at the methacholine PC(20) (Delta FVC) has been proposed as a surrogate marker of maximal airway response. The aim of this study was to compare the Delta FVC between patients with cough-variant asthma (CVA) and those with classic asthma (CA). We performed a retrospective analysis of methacholine challenge test data from 47 children who were diagnosed as having CVA and from 75 children who had CA of mild severity. The mean (+/- SD) Delta FVC was significantly (p = 0.001) lower in the CVA group (14.7 +/- 3.4%) compared with the CA group (17.1 +/- 4.4%), whereas PC(20) was not different between the two groups. Our results suggest that CVA is associated with a lower level of maximal airway response than CA.
ISSN
0277-0903 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17365202

https://hdl.handle.net/10371/22552
DOI
https://doi.org/10.1080/02770900601034379
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Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Immunology (면역학전공)Journal Papers (저널논문_면역학전공)
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