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Birth month and sensitization to house dust mites in asthmatic children
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yoo, Y. | - |
dc.contributor.author | Yu, J. | - |
dc.contributor.author | Kang, H. | - |
dc.contributor.author | Kim, D. K. | - |
dc.contributor.author | Koh, Y. Y. | - |
dc.contributor.author | Kim, C. K. | - |
dc.date.accessioned | 2009-12-24T11:12:18Z | - |
dc.date.available | 2009-12-24T11:12:18Z | - |
dc.date.issued | 2005-09-02 | - |
dc.identifier.citation | Allergy. 2005 Oct;60(10):1327-30. | en |
dc.identifier.issn | 0105-4538 (Print) | - |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16135003 | - |
dc.identifier.uri | https://hdl.handle.net/10371/22601 | - |
dc.description.abstract | BACKGROUND: Early exposure to high quantities of allergen has an important role in the incidence of atopic sensitization. In fact, subjects sensitized to house dust mites (HDMs) have a significantly higher proportion of births in the season when HDMs are most abundant. OBJECTIVE: The aim of this study was to investigate whether birth month patterns differ for asthmatic patients sensitized only to HDMs and for those sensitized to HDMs and other allergen(s). METHODS: Among 2225 patients with asthma, aged 10-16 years, 1642 sensitized to HDMs were identified by skin prick testing. This group was composed of patients sensitized only to HDMs (n = 715) and patients sensitized to HDMs and other allergen(s) (n = 927). The birth month distributions of the group of HDM-sensitive asthmatics or its subgroups were compared with that of a reference population (total live births in the same years as the studied subjects). The risk ratio of a given birth month in relation to all the other months was calculated as an odds ratio (OR) with the corresponding 95% confidence interval (CI). RESULTS: A significant difference in birth month distribution was observed for HDM-sensitive asthmatics (chi(2) = 23.6, P = 0.015), with higher rates of birth in August (OR: 1.23, 95% CI: 1.04-1.46) and September (1.24, 1.04-1.46). When the two subgroups were analyzed separately, significantly more births were noted in August (1.34, 1.06-1.71) and September (1.34, 1.05-1.70) for those sensitized only to HDMs, whereas no such birth month preference was observed for those sensitized to HDMs and other allergen(s). CONCLUSIONS: The HDM-positive asthmatics showed a greater proportion of births in August and September, which correspond to high HDM exposure. However, this birth month pattern was evident in asthmatic-sensitive only to HDMs, but was not observed in those sensitive to HDMs and other allergen(s). | en |
dc.language.iso | en | en |
dc.publisher | Wiley-Blackwell | en |
dc.subject | Adolescent | en |
dc.subject | Allergens/immunology | en |
dc.subject | Antigens, Dermatophagoides/*immunology | en |
dc.subject | Asthma/*epidemiology/immunology | en |
dc.subject | Child | en |
dc.subject | Female | en |
dc.subject | Humans | en |
dc.subject | Hypersensitivity, Immediate/*epidemiology/immunology | en |
dc.subject | Male | en |
dc.subject | Pyroglyphidae/*immunology | en |
dc.subject | Risk Factors | en |
dc.subject | Seasons | en |
dc.subject | Skin Tests | en |
dc.title | Birth month and sensitization to house dust mites in asthmatic children | en |
dc.type | Article | en |
dc.identifier.doi | 10.1111/j.1398-9995.2005.00856.x | - |
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