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Acne erythema improvement by long-pulsed 595-nm pulsed-dye laser treatment: a pilot study

Cited 18 time in Web of Science Cited 17 time in Scopus
Authors
Yoon, Ho Joon; Lee, Dong Hun; Kim, Sun Ok; Park, Kyoung Chan; Youn, Sang Woong
Issue Date
2008
Publisher
Taylor & Francis
Citation
J Dermatolog Treat. 2008;19(1):38-44
Keywords
Acne Vulgaris/pathology/*radiotherapyAdolescentAdultElasticity/radiation effectsErythema/pathology/*radiotherapyFemaleHumansLasers, Dye/adverse effects/*therapeutic useMalePilot ProjectsRadiation DosageSingle-Blind MethodSkin/pathologyStatistics, NonparametricTreatment Outcome
Abstract
OBJECTIVES: Recent studies have demonstrated that pulsed-dye laser (PDL) treatment is beneficial for inflammatory acne treatment. However, persistent erythema after inflammatory acne vulgaris ('acne erythema') remains a therapeutic challenge. The objectives of this study were to evaluate the clinical efficacy and safety of a long pulse duration 595-nm PDL (V-beam laser) therapy for the treatment of acne erythema. METHODS: Twenty patients with acne erythema were treated using two successive sessions with a 595-nm PDL at 4-week intervals. Overall acne severities were assessed using Leeds scores, degree of improvement using standardized digital photographs, erythema indexes and skin elasticity findings at baseline, and 4 weeks after each treatment. Patients' self-assessments were also recorded. RESULTS: A total of 90% of acne erythema patients achieved clinical improvement. Lesion counts decreased 24.9% after the first treatment (p<0.05) and by 57.6% (versus baseline) after the second treatment (p<0.05). Significant improvements were also noted in mean Leeds scores, erythema indexes, and skin elasticities after each treatment. Treatment-related pain was well-tolerated and adverse effects were limited to transient erythema and edema at treatment sites. CONCLUSION: A long pulse duration 595-nm PDL was found to improve acne erythema with minimal discomfort and an increase in skin elasticity.
ISSN
0954-6634 (Print)
Language
English
URI
http://www.informaworld.com/smpp/content~db=all?content=10.1080/09546630701646164

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18273723

https://hdl.handle.net/10371/23389
DOI
https://doi.org/10.1080/09546630701646164
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College of Medicine/School of Medicine (의과대학/대학원)Program in Clinical Pharmacology (협동과정-임상약리학전공)Journal Papers (저널논문_협동과정-임상약리학전공)
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