S-Space College of Medicine/School of Medicine (의과대학/대학원) Program in Clinical Pharmacology (협동과정-임상약리학전공) Journal Papers (저널논문_협동과정-임상약리학전공)
Acne erythema improvement by long-pulsed 595-nm pulsed-dye laser treatment: a pilot study
- Yoon, Ho Joon; Lee, Dong Hun; Kim, Sun Ok; Park, Kyoung Chan; Youn, Sang Woong
- Issue Date
- Taylor & Francis
- J Dermatolog Treat. 2008;19(1):38-44
- Acne Vulgaris/pathology/*radiotherapy; Adolescent; Adult; Elasticity/radiation effects; Erythema/pathology/*radiotherapy; Female; Humans; Lasers, Dye/adverse effects/*therapeutic use; Male; Pilot Projects; Radiation Dosage; Single-Blind Method; Skin/pathology; Statistics, Nonparametric; Treatment Outcome
- OBJECTIVES: Recent studies have demonstrated that pulsed-dye laser (PDL) treatment is beneficial for inflammatory acne treatment. However, persistent erythema after inflammatory acne vulgaris ('acne erythema') remains a therapeutic challenge. The objectives of this study were to evaluate the clinical efficacy and safety of a long pulse duration 595-nm PDL (V-beam laser) therapy for the treatment of acne erythema. METHODS: Twenty patients with acne erythema were treated using two successive sessions with a 595-nm PDL at 4-week intervals. Overall acne severities were assessed using Leeds scores, degree of improvement using standardized digital photographs, erythema indexes and skin elasticity findings at baseline, and 4 weeks after each treatment. Patients' self-assessments were also recorded. RESULTS: A total of 90% of acne erythema patients achieved clinical improvement. Lesion counts decreased 24.9% after the first treatment (p<0.05) and by 57.6% (versus baseline) after the second treatment (p<0.05). Significant improvements were also noted in mean Leeds scores, erythema indexes, and skin elasticities after each treatment. Treatment-related pain was well-tolerated and adverse effects were limited to transient erythema and edema at treatment sites. CONCLUSION: A long pulse duration 595-nm PDL was found to improve acne erythema with minimal discomfort and an increase in skin elasticity.
- 0954-6634 (Print)
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