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Abnormal liver function test predicts type 2 diabetes: a community-based prospective study

Cited 73 time in Web of Science Cited 76 time in Scopus
Authors
Cho, Nam H; Jang, Hak C; Choi, Sung Hee; Kim, Hyung R; Lee, Hong Kyu; Chan, Juliana C N; Lim, Soo
Issue Date
2007
Publisher
American Diabetes Association
Citation
Diabetes Care 30:2566-2568
Keywords
AdultAlanine Transaminase/bloodAspartate Aminotransferases/bloodBody Mass IndexDiabetes Mellitus, Type 2/*epidemiologyFemaleGlucose Tolerance TestHumansInsulin/bloodKorea/epidemiologyLiver Diseases/*complications*Liver Function TestsMaleMiddle AgedPredictive Value of TestsProspective StudiesReference ValuesRisk Factorsgamma-Glutamyltransferase/blood
Abstract
Increased activities of liver enzymes
such as aspartate aminotransferase
(AST), alanine aminotransferase
(ALT), and -glutamyltranspeptidase
(GGT) are indicators of hepatocellular injury.
Increased activity of these markers is
associated with insulin resistance (1),
metabolic syndrome, and type 2 diabetes
(2–9). However, most of these studies
were performed in Western countries (2–
5,7,9), and the two studies from Japan
and Korea were not community based
(6,8). In this prospective communitybased
study, we evaluated the relationships
between markers of liver function
and the onset of type 2 diabetes after adjusting
for potential risk factors including
inflammatory markers.
ISSN
1935-5548 (Electronic)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17626893

http://hdl.handle.net/10371/23401
DOI
https://doi.org/10.2337/dc07-0106
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College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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