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Pneumatosis intestinalis with pneumoperitoneum mimicking intestinal perforation in a patient with myelodysplastic syndrome after hematopoietic stem cell transplantation

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Authors
Keam, Bhumsuk; Lee, Jeong-Hoon; Oh, Myoung-Don; Kim, Inho; Yoon, Sung-Soo; Kim, Byoung Kook; Park, Seonyang
Issue Date
2007
Publisher
Korean Association of Internal Medicine
Citation
The Korean Journal of Internal Medicine 22(1):40-44.
Keywords
AdultDiagnosis, Differential*Hematopoietic Stem Cell TransplantationHumansIntestinal Perforation/*diagnosisMaleMyelodysplastic Syndromes/*diagnosis/pathologyPneumatosis Cystoides Intestinalis/*diagnosis/pathology/therapyPneumoperitoneum/*diagnosis
Abstract
Pneumatosis intestinalis (PI) is an uncommon disorder characterized by an accumulation of gas in the bowel wall, and has been associated with a variety of disorders and procedures. We describe a 35-year-old man who undertook hematopoietic stem cell transplantation due to myelodysplastic syndrome. An abdominal X-ray demonstrated extensive PI with pneumoperitoneum mimicking hollow organ perforation. However, the patient had no abdominal symptoms and there was no evidence of peritoneal inflammation. After two weeks of conservative management, including bowel rest and antibiotics, his pneumoperitoneum resolved spontaneously without any complications. Of the many factors that affect the gastrointestinal tract mucosal integrity, intramural pressure, and bacterial flora-produced intraluminal gas interact to produce PI. If the condition is accompanied by bowel ischemia, portomesenteric venous gas, metabolic acidosis, and abdominal sepsis, or if PI is severe in extent immediate surgical intervention is indicated. The described case supports that a mechanical rather than a bacterial etiology underlies the pathogenesis of PI.
ISSN
1226-3303 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17427646

https://hdl.handle.net/10371/27168
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College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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