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Cigarette smoking and risk of lung cancer in Korean men: the Seoul Male Cancer Cohort Study

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Authors
Bae, Jong-Myon; Lee, Moo-Song; Shin, Myung-Hee; Kim, Dong-Hyun; Li, Zhong-Min; Ahn, Yoon-Ok
Issue Date
2007-06-29
Publisher
Korean Academy of Medical Science
Citation
J Korean Med Sci 2007; 22: 508-12
Keywords
Lung NeoplasmCohort StudiesFollow-Up StudiesCancer IncidenceCigarette SmokingMiddle AgedProportional Hazards ModelsRiskRisk Factors*SmokingTreatment Outcome
Abstract
Lung cancer is the leading cause of cancer deaths in Korea. The aim of this study was to estimate lung cancer risk of cigarette smoking in Korean men by a 10-yr follow-up prospective cohort study using the primary databases. The number of subjects was 14,272 men, who had full information of smoking habits among participants in the Seoul Male Cancer Cohort Study (SMCC). Total 125,053 person-years were calculated by determining the number of days from the start of followup, January 1, 1993, until the date of lung cancer diagnosis, death from another cause, or the end of follow-up, December 31, 2002, followed by converting the number of days to years. The information of outcome was obtained by the database of Korea Central Cancer Registry, Seoul Regional Cancer Registry, and Korea Statistical Office. The relative risk (RR) and its 95% confidence interval (CI) values of smoking were calculated using Cox proportional hazards regression stratified on potential confounders. During the follow-up periods, 78 cases of lung cancer occurred. The cigarette smoking is the major risk factor and increases the 4.18-fold risk of lung cancer in Korean men. In order to control lung cancer, intervention of quitting smoking is needed.
ISSN
1011-8934 (Print)
Language
English
URI
http://ukpmc.ac.uk/articlerender.cgi?tool=pubmed&pubmedid=17596662

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17596662

https://hdl.handle.net/10371/28536
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College of Medicine/School of Medicine (의과대학/대학원)Preventive Medicine (예방의학전공)Journal Papers (저널논문_예방의학전공)
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