S-Space College of Medicine/School of Medicine (의과대학/대학원) Preventive Medicine (예방의학전공) Journal Papers (저널논문_예방의학전공)
Risk factor analysis for development of asymptomatic carotid stenosis in Koreans
- Lim, Yun Jeong; Kim, Young-Wook; Choe, Yeon Kyan; Ki, Chang-Seok; Park, Sue Kyung
- Issue Date
- Korean Academy of Medical Science
- J Korean Med Sci. 2006 Feb;21(1):15-9.
- Adult; Age Factors; Aged; Carotid Stenosis/blood/*epidemiology/etiology; Cholesterol/blood; Cholesterol, LDL/blood; Female; Humans; Korea/epidemiology; Logistic Models; Male; Middle Aged; Multivariate Analysis; Prevalence; Retrospective Studies; Risk Factors; Smoking/adverse effects
- Many risk factors for atherosclerosis have been proposed to identify high risk individuals. We conducted a retrospective study to determine the risk factors for development of carotid stenosis (CS) in Koreans. Database of 2,805 subjects who underwent a check up of carotid artery for health examination were analyzed. Stenosis (%) of common carotid artery or proximal internal carotid artery was examined with ultrasonography. Subjects were divided into 2 groups (Group I; CS <10%, Group II; CS >or= 30%). We compared demographic, laboratory and clinical data between 2 groups to determine the risk factors of CS. One hundred ninety seven subjects (7.0%) were categorized as Group II. At age- and sex-adjusted multivariate analysis, diabetes mellitus, hypertension, cerebrovascular disease, ischemic heart disease, hyperlipidemia, aspirin medication, current smoking, fasting glucose, total cholesterol, low density lipoprotein-cholesterol (LDL-C) and leukocyte count were significant risk factors of CS. At stepwise logistic regression analysis, age, hypertension, hyperlipidemia, LDL-C and leukocyte count were independent risk factors. At subgroup analysis by smoking, age and leukocyte count were independent risk factors in smoker and age and hypertension in nonsmoker.
- 1011-8934 (Print)