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Correlation of bispectral index with end-tidal sevoflurane concentration and age in infants and children
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, H. S. | - |
dc.contributor.author | Oh, A. Y. | - |
dc.contributor.author | Kim, C. S. | - |
dc.contributor.author | Kim, S. D. | - |
dc.contributor.author | Seo, K. S. | - |
dc.contributor.author | Kim, J. H. | - |
dc.date.accessioned | 2010-01-12T06:58:58Z | - |
dc.date.available | 2010-01-12T06:58:58Z | - |
dc.date.issued | 2005-07-19 | - |
dc.identifier.citation | Br J Anaesth. 2005 Sep;95(3):362-6. Epub 2005 Jul 15. | en |
dc.identifier.issn | 0007-0912 (Print) | - |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16024583 | - |
dc.identifier.uri | https://hdl.handle.net/10371/29747 | - |
dc.description.abstract | BACKGROUND: The bispectral index (BIS) has been evaluated as a tool for measuring depth of anaesthesia, but the use of BIS in a paediatric population is still controversial. This study was designed to evaluate the correlation of BIS with end-tidal sevoflurane concentration and age in infants and children. METHODS: Eighty-one patients undergoing elective urology surgery were allocated into three age groups; 6 months to 2 yr (n=28), 3-7 yr (n=33), and 8-12 yr (n=20). Sevoflurane was administered to achieve steady-state end-tidal sevoflurane concentrations (ET(sevo)) of 2.0, 3.0, and 4.0%; these were achieved consecutively either from the lowest or from the highest concentration. The BIS (version XP) was monitored continuously. RESULTS: In all three groups, BIS decreased significantly when ET(sevo) increased from 2.0 to 3.0% but there was a paradoxical increase in BIS values when ET(sevo) increased from 3.0 to 4.0%. The non-linear regression analysis showed a significant correlation between BIS and age at each ET(sevo). The younger patients showed the higher BIS values. CONCLUSIONS: In children aged 6 months to 12 yr, the BIS increased paradoxically as ET(sevo) increased from 3.0 to 4.0%. BIS values showed a wide variation in the same ET(sevo) and the age itself was considered to be a factor affecting the BIS values. | en |
dc.language.iso | en | en |
dc.publisher | Oxford University Press | en |
dc.subject | Aging/*physiology | en |
dc.subject | Anesthetics, Inhalation/*pharmacology | en |
dc.subject | Blood Pressure/drug effects | en |
dc.subject | Child | en |
dc.subject | Child, Preschool | en |
dc.subject | Dose-Response Relationship, Drug | en |
dc.subject | Electroencephalography/*drug effects | en |
dc.subject | Heart Rate/drug effects | en |
dc.subject | Humans | en |
dc.subject | Infant | en |
dc.subject | Methyl Ethers/*pharmacology | en |
dc.subject | Monitoring, Intraoperative/*methods | en |
dc.subject | Prospective Studies | en |
dc.subject | Regression Analysis | en |
dc.subject | Urologic Surgical Procedures | en |
dc.title | Correlation of bispectral index with end-tidal sevoflurane concentration and age in infants and children | en |
dc.type | Article | en |
dc.identifier.doi | 10.1093/bja/aei196 | - |
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