Browse
S-Space
College of Medicine/School of Medicine (의과대학/대학원)
Nuclear Medicine (핵의학전공)
Journal Papers (저널논문_핵의학전공)
Dopamine transporter SPECT of a liver cirrhotic with atypical parkinsonism
- Authors
- Kim, Jongchul; Kim, Jong-Min; Kim, Yu Kyeong; Shin, Jung Woo; Choi, Seong Hoon; Kim, Sang Eun; Kim, Yangho
- Issue Date
- 2007
- Publisher
- National Institute of Industrial Health
- Citation
- Industrial Health 45(3): 497-500
- Keywords
- Adult; Diagnosis, Differential; *Dopamine Plasma Membrane Transport Proteins; Globus Pallidus; Humans; *Liver Cirrhosis; Male; Manganese/*toxicity; Parkinsonian Disorders/*diagnosis/physiopathology; Tomography, Emission-Computed, Single-Photon/*instrumentation
- Abstract
- High level of exposure to manganese (Mn) can cause a clinically and pathophysiologically distinct syndrome from idiopathic Parkinson's disease (PD). We describe the clinical features and results of [123I]-fluoropropyl (FP)-CIT SPECT of a liver cirrhotic with atypical parkinsonism. The patient developed atypical parkinsonian features associated with elevated blood Mn from hepatic dysfunction. [123I]-FP-CIT brain SPECT images of dopamine transporter (DAT) demonstrated overall normal range of DAT uptake in the striatum although there were scattered small hypodense regions. The globus pallidum had increased signal on T1-weighted magnetic resonance imaging (MRI). All these findings are compatible with those of manganism, and are remarkably different from that in PD.
- ISSN
- 0019-8366 (Print)
- Language
- English
- URI
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17634700
http://hdl.handle.net/10371/29862
- Files in This Item:
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.