Publications
Detailed Information
Scoring system for predicting malignancy in patients diagnosed with atypical ductal hyperplasia at ultrasound-guided core needle biopsy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ko, Eunyoung | - |
dc.contributor.author | Han, Wonshik | - |
dc.contributor.author | Lee, Jong Won | - |
dc.contributor.author | Cho, Jihyoung | - |
dc.contributor.author | Kim, Eun-Kyu | - |
dc.contributor.author | Jung, So-Youn | - |
dc.contributor.author | Kang, Mee Joo | - |
dc.contributor.author | Moon, Woo Kyung | - |
dc.contributor.author | Park, In Ae | - |
dc.contributor.author | Kim, Sung-Won | - |
dc.contributor.author | Kim, Ku Sang | - |
dc.contributor.author | Lee, Eun Sook | - |
dc.contributor.author | Min, Kyu Hong | - |
dc.contributor.author | Noh, Dong-Young | - |
dc.date.accessioned | 2009-05-27 | - |
dc.date.available | 2009-05-27 | - |
dc.date.issued | 2007-12-04 | - |
dc.identifier.citation | Breast Cancer Res Treat 112(1):189-195 | en |
dc.identifier.issn | 0167-6806 (print) | - |
dc.identifier.issn | 1573-7217 (online) | - |
dc.identifier.uri | https://hdl.handle.net/10371/3871 | - |
dc.description | The original publication is available at www.springerlink.com. | en |
dc.description.abstract | BACKGROUND: The aim of this study was to determine factors that predict under-evaluation of malignancy in patients diagnosed with atypical ductal hyperplasia (ADH) at ultrasound-guided core needle biopsy (CNB), and to develop a prediction algorithm for scoring the possibility of a diagnosis upgrade to malignancy based on clinical, radiological and pathological factors. METHODS: The study enrolled patients diagnosed with ADH at ultrasound-guided CNB who subsequently underwent surgical excision of the lesion. Multivariate analysis was used to identify relevant clinical, radiological and pathological factors that may predict malignancy. RESULTS: A total of 102 patients with ADH at CNB were identified. Of the 74 patients who underwent subsequent surgical excision, 34 (45.8%) were diagnosed with invasive or in situ malignant foci. Multivariate analysis revealed that age>50 years, microcalcification on mammography, size on imaging>15 mm and a palpable lesion were independent predictors of malignancy. Focal ADH was a negative predictor. A scoring system was developed based on logistic regression models and beta coefficients for each variable. The area under the ROC curve was 0.903 (95% CI: 0.82-0.94), and the negative predictive value was 100% for a score | en |
dc.language.iso | en | - |
dc.publisher | Springer Verlag | en |
dc.subject | ADH underestimation | en |
dc.subject | Atypical ductal hyperplasia | en |
dc.subject | Core needle biopsy | en |
dc.subject | Scoring system | en |
dc.subject | Ultrasound-guidance | en |
dc.title | Scoring system for predicting malignancy in patients diagnosed with atypical ductal hyperplasia at ultrasound-guided core needle biopsy | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 고은영 | - |
dc.contributor.AlternativeAuthor | 한원실 | - |
dc.contributor.AlternativeAuthor | 이종원 | - |
dc.contributor.AlternativeAuthor | 조지형 | - |
dc.contributor.AlternativeAuthor | 김은규 | - |
dc.contributor.AlternativeAuthor | 정소윤 | - |
dc.contributor.AlternativeAuthor | 강미주 | - |
dc.contributor.AlternativeAuthor | 문우경 | - |
dc.contributor.AlternativeAuthor | 박인애 | - |
dc.contributor.AlternativeAuthor | 김성원 | - |
dc.contributor.AlternativeAuthor | 김구상 | - |
dc.contributor.AlternativeAuthor | 이은숙 | - |
dc.contributor.AlternativeAuthor | 민규홍 | - |
dc.contributor.AlternativeAuthor | 노동영 | - |
dc.identifier.doi | 10.1007/s10549-007-9824-0 | - |
dc.identifier.doi | 10.1007/s10549-007-9824-0 | - |
dc.citation.journaltitle | Breast Cancer Research and Treatment | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.