S-Space College of Medicine/School of Medicine (의과대학/대학원) Anesthesiology and Pain Medicine (마취통증의학전공) Journal Papers (저널논문_마취통증의학전공)
Increased non-stationarity of heart rate during general anaesthesia with sevoflurane or desflurane in children
- Yum, M-K; Kim, J-T; Kim, H-S
- Issue Date
- Oxford University Press
- Br J Anaesth. 2008 Jun;100(6):772-9. Epub 2008 Apr 9.
- Adolescent; Anesthetics, Inhalation/*pharmacology; Biological Clocks/drug effects; Child; Child, Preschool; Electrocardiography/drug effects; Female; Heart Rate/*drug effects; Humans; Infant; Intraoperative Period; Isoflurane/*analogs & derivatives/pharmacology; Male; Methyl Ethers/*pharmacology; Monitoring, Intraoperative/methods; Signal Processing, Computer-Assisted
- BACKGROUND: During general anaesthesia, the most prominent change in heart rate variability (HRV) is a decrease in the magnitude of heart rate (HR) oscillation in the high- and low-frequency ranges. In children receiving sevoflurane or desflurane, we observed a significant increase in HR non-stationarity, that is, a significant change of mean HR over time. The aim of our study was to describe this increased non-stationarity and compare it with the decrease in the magnitude of HR oscillation. METHODS: Sixty children received sevoflurane (n=30) or desflurane anaesthesia (n=30). The magnitude of HR oscillation and non-stationarity during pre-anaesthesia and anaesthesia were measured by spectral and Hurst analyses using structure function, respectively. RESULTS: Low- and high-frequency powers decreased significantly and the very-short-term (2
- 1471-6771 (Electronic)
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