Browse

관중의 항균작용 및 세포독성에 관한 연구

DC Field Value Language
dc.contributor.author김승남-
dc.contributor.author구영-
dc.contributor.author류인철-
dc.contributor.author함병도-
dc.contributor.author배기환-
dc.contributor.author한수부-
dc.contributor.author정종평-
dc.contributor.author최상묵-
dc.date.accessioned2010-02-01T06:06:50Z-
dc.date.available2010-02-01T06:06:50Z-
dc.date.issued2000-
dc.identifier.citation대한치주과학회지 2000 30;83-91en
dc.identifier.issn0250-3352-
dc.identifier.urihttp://uci.or.kr/ G100:I100-KOI(KISTI1.1003/JNL.JAKO200021452720869)-
dc.identifier.urihttps://hdl.handle.net/10371/47331-
dc.description.abstractThe purpose of this study was to evaluate the antimicrobial activity of Crassirhzimae rhizoma and its possible use as an oral antiseptics for prevention of periodontitis. Its antibacterial activity against periodontopathic microorganisms including Actinobacillus actiomycetem - comitans, Capnocytophaga ochracea, Streptococcus mutans, Porphyromonas gingivalis, Prevotella intermedia, Actinomyces viscosus, Fusobacterium nucleatumwas evaluated via modified stab culture method. The cytotoxicity against gingival fibroblasts and rat osteoblasts was investigated via [$^3H$]thymidine incorporation and cellular activity was investigated via MTT assay. Chlorhexidine was used as control group. Crassirhizomae rhizoma was prepared at concentrations of 0.2, 0.15, 0.1, 0.05%. Chlorhexidine was also prepared at the same concentration. Crassirhizomae rhizoma showed lower antimicrobial antivity against these microorganism than chlorhexidine, but this difference was not significant. And, Crassirhzomae rhizoma showed more cellular activity and less cytotoxicity than chlorhexidine on human gingival fibrablast and rat osteoblast. This study suggests that Crassirhzomae rhizoma might be a candidate for a safe oral antiseptic for the prevention and treatment of periodontal disease.en
dc.description.sponsorship이 연구는 1997년도 서울대학교 병원지정연구비 지원에 의한 결과입니다.en
dc.language.isokoen
dc.publisher대한치주과학회en
dc.subjectnatural extracten
dc.subjectChassizomae rhizomaen
dc.subjectantibacterial effecten
dc.subjectcytotoxicityen
dc.title관중의 항균작용 및 세포독성에 관한 연구en
dc.typeArticleen
Appears in Collections:
College of Dentistry/School of Dentistry (치과대학/치의학대학원)Dept. of Dentistry (치의학과)Journal Papers (저널논문_치의학과)
Files in This Item:
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse