S-Space College of Dentistry/School of Dentistry (치과대학/치의학대학원) Dept. of Dentistry (치의학과) Journal Papers (저널논문_치의학과)
수종의 생분해성 차폐막의 생체분해도 및 조직재생유도능력에 관한 연구
- Issue Date
- 대한치주과학회지 27 : 151-163, 1997.
- synthetic biodegradable membrane ; biodegradability ; biocompatibility ; tissue regenerative capacity:guided bone regeneration
- The purpose of this study was to evaluate on the biodegradability, biocompatibility and tissue regenerative capacity of synthetic biodegradable , and . To evaluate the cell attachment on the membranes, in vitro, the number of gingival fibroblasts attached to each membrane was counted by hemocytometer. Cytotoxicity test for the membranes was performed by MTT test with gingival fibroblast For evaluation of guided- bone regenerative potential, the amount of new bone formation in the rat calvarial defects(5mm in diameter) beneath the membranes was observed for two weeks and examined of the specimens by Massons trichrome staining. Biodegradability was observed for 2, 4, 8 and 12 weeks after implantation of each materials under the skin of rats and examined the specimens with H & E staining. The number of cell attachment were the greatest in and followed by . Cell viability of three membranes was almost similar levels. Biodegradability of was the highest among three membrane and the potential of guided bone regeneration was the greatest in the and was followed. These results suggested that commercially available biodegradable membranes were non-toxic and highly potential to guided bone regeneration.
- http://uci.or.kr/ G100:I100-KOI(KISTI1.1003/JNL.JAKO199721452720288)