S-Space College of Medicine/School of Medicine (의과대학/대학원) Dept. of Medicine (의학과) The Seoul Journal of Medicine The Seoul Journal of Medicine Vol. 34 No.4 (1993)
Detection of Human Papillomavirus(HPV) DNA in Children's Genital and Respiratory Tract Papilloma and in Birth Canals of Their Mothers
- Jung, Seung Yong; Oh, Jun Kyu; Lee, Yong Suk; Park, Kyoung Chan; Kim, Kwang Hyun
- Issue Date
- Seoul J Med, Vol.34 No.4, pp. 311-314
- In order to study the epidemiologic relationship between children's
papillomaviral disease and papillomaviral infection of mothers, five anogenital warts
and seven laryngeal papilloma in children were analyzed by polymerase chain reaction
to detect HPV DNA HPV type 6 was found in 8 cases and HPV type 11 in 7 cases.
Both types were found in 3 cases. From these results, anogenital warts and laryngeal
papilloma in children are found to be pure viral diseases caused by HPV type 6 and 11.
Nine cases of DNA extracted from cervical swabs from mothers of children with
condyloma or laryngeal papilloma, were examined to identify possible latent infection
of HPV. Among 9 cases, HPV DNA was found in two cases. These results suggest that
inapparent infection of HPV type 6, 11 in the birth canal may contribute to the development
of these viral diseases in their offspring aside from sexual abuse.