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Morphological Development of the Human Fetal Lung : 한국인 태아폐(胎兒肺)의 형태학적 발육에 관한 연구
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Hoan Jong | - |
dc.contributor.author | Chi, Je G. | - |
dc.contributor.author | Ko, Kwang Wook | - |
dc.date.accessioned | 2009-07-14T08:07:47Z | - |
dc.date.available | 2009-07-14T08:07:47Z | - |
dc.date.issued | 1986-03 | - |
dc.identifier.citation | Seoul J Med, Vol.27 No.1, pp. 75-90 | - |
dc.identifier.issn | 0582-6802 | - |
dc.identifier.uri | https://hdl.handle.net/10371/5497 | - |
dc.description.abstract | The morphological development of the human fetal lung was studied analysing
a total of 198 human fetal lungs, including lungs of 16 embryos. The weight of the lung increased progressively from 0.7 gm at 9-12 weeks of gestation to 45.2 gm at 37-40 weeks, and the right lung constituted 54 % of total lung weight. The lung, fixed in the inflated state with negative pressure of 24-25 em H20 , increased rapidly in its volume at 24-25 weeks of gestation, coinciding with the development of saccules. Reconstruction of the embryonal lungs revealed the presence of lung buds at 4 weeks, stem bronchi at 5 weeks, segmental bronchi at 6 weeks, and subsegmental bronchi thereafter. Histological characteristics were analysed with special emphasis on sequential development of the functioning respiratory units. The period of 4-8 weeks was characterized by budding of large bronchi and appearance of pleura and lobar pattern. During the period of 9-16 weeks, conducting airways were laid down associated with development of cilia and mucous glands. At the period of 17 -28 weeks acinar canals were proliferating and were followed by flattening of epithelium and vascularization. Well developed saccules appeared by the end of this period. During the period of 29-36 weeks, progressive thinning of septa was noted, accompanied by segmentation of saccules by developing secondary crests. As a result well developed alveoli with delicate septum and a single capillary system could be identified at the period of 37 -40 weeks. The height of the epithelium at the terminal buds showed gradual decrease from 36 f1 m at 5 weeks to 5.8 J1 m at 21 weeks of gestation. | - |
dc.language.iso | en | - |
dc.publisher | Seoul National University College of Medicine | - |
dc.subject | Fetus | - |
dc.subject | Lung | - |
dc.subject | Embryology | - |
dc.title | Morphological Development of the Human Fetal Lung | - |
dc.title.alternative | 한국인 태아폐(胎兒肺)의 형태학적 발육에 관한 연구 | - |
dc.type | SNU Journal | - |
dc.contributor.AlternativeAuthor | 이환종 | - |
dc.contributor.AlternativeAuthor | 지제근 | - |
dc.contributor.AlternativeAuthor | 고광욱 | - |
dc.citation.journaltitle | 서울 의대 잡지 | - |
dc.citation.journaltitle | 서울 의대 학술지 | - |
dc.citation.journaltitle | Seoul Journal of Medicine | - |
dc.citation.endpage | 90 | - |
dc.citation.number | 1 | - |
dc.citation.pages | 75-90 | - |
dc.citation.startpage | 75 | - |
dc.citation.volume | 27 | - |
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