Browse

Vascular Changes in Relation with Tumor Regression Induced by Combined Oral Administration of Heparin and Hydrocortisone
헤파린과 하이드로코티손의 병합경구투여에 의한 종양퇴화과정에서의 혈관변화

Cited 0 time in Web of Science Cited 0 time in Scopus
Authors
Park, Sang Chul; Lee, Jung Bin
Issue Date
1986-12
Publisher
Seoul National University College of Medicine
Citation
Seoul J Med, Vol.27 No.4, pp. 313-318
Keywords
Vascular changeTumor regressionHeparinHydrocortisone
Abstract
The oral administration of heparin and hydrocortisone inhibited the tumor
growth and induced the regression of the solid myeloma implanted on the back of BalbC
mice. The inhibition of tumor growth was dependent on the regimen, which was suggested by
the reactivation of tumor growth with interruption of the theraphy. The histologic analysis of
those tumors revealed intravascular deposition of fibrillary eosinophilic substances and necrosis
of tumors as well as the thickening of the vascular wall. The present experiment confirmed the
tumor inhibition effect of Folkman's heparin and hydrocortisone treatment and found that the
regimen could induce the vascular change in addition to the proposed angiogenesis inhibition.
ISSN
0582-6802
Language
English
URI
https://hdl.handle.net/10371/5521
Files in This Item:
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 27 No.4 (1986)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse