S-Space College of Medicine/School of Medicine (의과대학/대학원) Dept. of Medicine (의학과) The Seoul Journal of Medicine The Seoul Journal of Medicine Vol. 30 No.3 (1989)
Listeriosis in a Stillborn Fetus (An Autopsy Case)
사산아에서 발견된 리스테리아증 (1부검례)
- Chi, Je G.
- Issue Date
- Seoul J Med, Vol.30 No.3, pp. 181-188
- Listeriosis is an infectious disease of animals and man that is characterized by
a wide specturm of clinical manifestations. Miliary granulomatosis is unique features of listeria
infection in deadborn fetuses and enwborn infants.
This report deals with an autopsy case of miliary granulomatosis in a deadborn fetus,
which was thought to be due to listeria infection. The liver and spleen were enlarged and
showed disseminated miliary speckles. Microscopically these nodules were composed of
necrotizing granulomas showinq central necrosis with nuclear debris and peripheral epithelioid
cell collections. In the centers of the lesions there were numerous micro-organisms in
clusters or isolated, that showed gram-posivity on Brown-Brenn stain and dark elongated
structures on Warthin-Starry satin. These miliary granulomas were also seen in the lungs.
intestinal tract, liver, adrenals, spleen and bone marrow.