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Angiomyolipoma of the Kidney: Its Positive Expression of Immunohistochemical Markers for Schwann Cell Differentiation : 신의 혈관근지방종에 있어서의 슈반세포형 면역조직화확적 표지의 발현
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- Authors
- Issue Date
- 1989-12
- Citation
- Seoul J Med, Vol.30 No.4, pp. 223-229
- Keywords
- Angiomyolipoma ; Immunohistochemistry ; S-100 protein ; Neuron specific enolase ; Desmin ; Neural differentiation
- Abstract
- Ten cases of renal angiomyolipomas were immunohistochemically analyzed
for the presence of S-100 protein, neuron specific enolase (NSE) and desmin using the
avidin-biotin complex method. The composition of histologic constituents differed in each
case. The cases with predominantly smooth muscle-like solid spindle cell proliferation
showed unexpected positive reaction to S-100 protein and NSE. Among 10 cases, five were
both S-100 protein positive and NSE positive. The reaction pattern of S-100 protein and
NSE was similar. Relatively weak or minimal positive reactions to desmin were observed in
the cases and the distribution of positive reaction was different from those of S-100 protein
and NSE. The result demonstrated immunohistochemical evidence of neural or Schwarm cell
differentiation in a significant proportion of renal angiomyolipomas, and its histogenesis was
speculated.
- ISSN
- 0582-6802
- Language
- English
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