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Signet Ring Cell Carcinoma of the Stomach in N-methyl-N'nitro-N-nitrosoguanidine-Administered Rats. Report of Two Cases with Special Reference to Its Histogenesis : N-methyl-N'-Nitrosoguanidine 투여에 의하여 발생한 흰쥐 위의 인환세포암종.선와상피세포로부터의 조직발생을 시사하는 2 증례보고
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Yong Il | - |
dc.contributor.author | Kim, Woo Ho | - |
dc.contributor.author | Han, Duck Jong | - |
dc.date.accessioned | 2009-07-17T05:04:08Z | - |
dc.date.available | 2009-07-17T05:04:08Z | - |
dc.date.issued | 1987-03 | - |
dc.identifier.citation | Seoul J Med, Vol.28 No.1, pp. 10-15 | - |
dc.identifier.issn | 0582-6802 | - |
dc.identifier.uri | https://hdl.handle.net/10371/5692 | - |
dc.description.abstract | Sprague-Dawley rats, orally administered with N-methyl-N'-nitro-N-nitrosoguanidine
(100 ,u glml dissolved in drinking water given ad libitum) for 28 weeks were sacrificed 12 weeks after the last administration. Of 89 neoplastic lesions from 96 rats, two rats developed signet ring cell carcinoma (SRC) with focal mixture of poorly differentiated adenocarcinoma in one, involving the full thickness of the gastric wall and blood vessels. Aside from the incipient atypical cell growth along the foveolar epithelium there was a histochemical similarity of mucin between SRC and atypical foveolar epithelial cells. These observations suggest that SRC develops from non-metaplastic foveolar epithelium of the stomach. | - |
dc.language.iso | en | - |
dc.publisher | Seoul National University College of Medicine | - |
dc.subject | Experimental gastric carcinoma | - |
dc.subject | Signet ring cell carcinoma | - |
dc.subject | N-methyl-N'-nitro-N-nitrosoguanidine | - |
dc.title | Signet Ring Cell Carcinoma of the Stomach in N-methyl-N'nitro-N-nitrosoguanidine-Administered Rats. Report of Two Cases with Special Reference to Its Histogenesis | - |
dc.title.alternative | N-methyl-N'-Nitrosoguanidine 투여에 의하여 발생한 흰쥐 위의 인환세포암종.선와상피세포로부터의 조직발생을 시사하는 2 증례보고 | - |
dc.type | SNU Journal | - |
dc.contributor.AlternativeAuthor | 김용일 | - |
dc.contributor.AlternativeAuthor | 김우호 | - |
dc.contributor.AlternativeAuthor | 한덕종 | - |
dc.citation.journaltitle | 서울 의대 잡지 | - |
dc.citation.journaltitle | 서울 의대 학술지 | - |
dc.citation.journaltitle | Seoul Journal of Medicine | - |
dc.citation.endpage | 15 | - |
dc.citation.number | 1 | - |
dc.citation.pages | 10-15 | - |
dc.citation.startpage | 10 | - |
dc.citation.volume | 28 | - |
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