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Plasma-treated silk fibroin nanofibers for skin regeneration

Cited 72 time in Web of Science Cited 79 time in Scopus
Authors
Min, Byung-Moo; Jeong, Lim; Yeo, In-Sung; Kim, Ha Na; Yoon, Young Il; Jang, Da Hyun; Jung, Sung Youn; Park, Won Ho
Issue Date
2009-04
Publisher
Elsevier
Citation
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 44 (2009) 222-228.
Keywords
Silk fibroinElectrospinningNanofiberPlasma treatmentCell behavior
Abstract
Silk fibroin (SF) nanofibers were prepared by electrospinning and treated with plasma in the presence of oxygen or methane gas to modify their surface characteristics. The surface characteristics of the SF nanofibers after plasma treatment were examined using contact angle measurements and XPS analysis. The hydrophilicity of the electrospun SF nanofibers decreased slightly by the CH4 plasma treatment. On the other hand, the hydrophilicity of the SF nanofibers increased greatly by an O2 plasma treatment. The O2-treated SF nanofibers showed higher cellular activities for both normal human epidermal keratinocytes (NHEK) and fibroblasts (NHEF) than the untreated ones.
ISSN
0141-8130
Language
English
URI
https://hdl.handle.net/10371/62156
DOI
https://doi.org/10.1016/j.ijbiomac.2008.12.008
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College of Dentistry/School of Dentistry (치과대학/치의학대학원)Dept. of Dentistry (치의학과)Journal Papers (저널논문_치의학과)
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