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Enhancing the estimation of blood pressure using pulse arrival time and two confounding factors

Cited 29 time in Web of Science Cited 28 time in Scopus
Authors
Baek, Hyun Jae; Kim, Ko Keun; Kim, Jung Soo; Lee, Boreom; Park, Kwang Suk
Issue Date
2010-02
Publisher
IOP Publishing
Citation
Physiol. Meas. 31 (2010) 145–157
Keywords
BPPATheart ratearterial stiffnessmultiple-regression analysis
Abstract
A new method of blood pressure (BP) estimation using multiple regression
with pulse arrival time (PAT) and two confounding factors was evaluated
in clinical and unconstrained monitoring situations. For the first analysis
with clinical data, electrocardiogram (ECG), photoplethysmogram (PPG) and
invasive BP signals were obtained by a conventional patient monitoring device
during surgery. In the second analysis, ECG, PPG and non-invasive BP were
measured using systems developed to obtain data under conditions in which
the subject was not constrained. To enhance the performance of BP estimation
methods, heart rate (HR) and arterial stiffness were considered as confounding
factors in regression analysis. The PAT and HR were easily extracted from
ECG and PPG signals. For arterial stiffness, the duration from the maximum
derivative point to the maximum of the dicrotic notch in the PPG signal, a
parameter called TDB, was employed. In two experiments that normally cause
BP variation, the correlation between measured BP and the estimated BP was
investigated. Multiple-regression analysis with the two confounding factors
improved correlation coefficients for diastolic blood pressure and systolic blood
pressure to acceptable confidence levels, compared to existing methods that
consider PAT only. In addition, reproducibility for the proposed method was
determined using constructed test sets. Our results demonstrate that noninvasive,
non-intrusive BP estimation can be obtained using methods that can
be applied in both clinical and daily healthcare situations.
ISSN
0967-3334
Language
English
URI
http://hdl.handle.net/10371/62286
DOI
https://doi.org/10.1088/0967-3334/31/2/002
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College of Engineering/Engineering Practice School (공과대학/대학원)Program in Bioengineering (협동과정-바이오엔지니어링전공)Journal Papers (저널논문_협동과정-바이오엔지니어링전공)
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