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Chitosan sponges as tissue engineering scaffolds for bone formation
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Seol, Yang-Jo | - |
dc.contributor.author | Lee, Jue-Yeon | - |
dc.contributor.author | Park, Yoon-Jeong | - |
dc.contributor.author | Lee, Yong-Moo | - |
dc.contributor.author | Ku, Young | - |
dc.contributor.author | Rhyu, In-Chul | - |
dc.contributor.author | Lee, Seung-Jin | - |
dc.contributor.author | Han, Soo-Boo | - |
dc.contributor.author | Chung, Chong-Pyoung | - |
dc.date.accessioned | 2010-04-01T07:53:40Z | - |
dc.date.available | 2010-04-01T07:53:40Z | - |
dc.date.issued | 2004-07 | - |
dc.identifier.citation | Biotechnol Lett. 26(13):1037-41. | en |
dc.identifier.issn | 0141-5492 | - |
dc.identifier.uri | https://hdl.handle.net/10371/62337 | - |
dc.description.abstract | Rat calvarial osteoblasts were grown in porous chitosan sponges fabricated by freeze drying. The prepared chitosan sponges had a porous structure with a 100-200 microm pore diameter, which allowed cell proliferation. Cell density, alkaline phosphatase activity and calcium deposition were monitored for up to 56 d culture. Cell numbers were 4 x 10(6) (day 1), 11 x 10(6) (day 28) and 12 x 10(6) (day 56) per g sponge. Calcium depositions were 9 (day 1), 40 (day 28) and 48 (day 56) microg per sponge. Histological results corroborated that bone formation within the sponges had occurred. These results show that chitosan sponges can be used as effective scaffolding materials for tissue engineered bone formation in vitro. | en |
dc.description.sponsorship | This work was supported by a grant from the Ministry
of Science and Technology (MOST), #98-N1-02-01- A-13, Republic of Korea. | en |
dc.language.iso | en | en |
dc.publisher | Springer Verlag | en |
dc.subject | bone formation | en |
dc.subject | chitosan sponges | en |
dc.subject | osteoblast | en |
dc.subject | tissue engineering | en |
dc.title | Chitosan sponges as tissue engineering scaffolds for bone formation | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 설양조 | - |
dc.contributor.AlternativeAuthor | 이주연 | - |
dc.contributor.AlternativeAuthor | 박윤정 | - |
dc.contributor.AlternativeAuthor | 이용무 | - |
dc.contributor.AlternativeAuthor | 류인철 | - |
dc.contributor.AlternativeAuthor | 이승진 | - |
dc.contributor.AlternativeAuthor | 한수범 | - |
dc.contributor.AlternativeAuthor | 구영 | - |
dc.identifier.doi | 10.1023/B:BILE.0000032962.79531.fd | - |
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