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Computer-aided detection in full-field digital mammography: sensitivity and reproducibility in serial examinations
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Seung Ja | - |
dc.contributor.author | Moon, Woo Kyung | - |
dc.contributor.author | Cho, Nariya | - |
dc.contributor.author | Cha, Joo Hee | - |
dc.contributor.author | Kim, Sun Mi | - |
dc.contributor.author | Im, Jung-Gi | - |
dc.date.accessioned | 2010-04-02T01:54:52Z | - |
dc.date.available | 2010-04-02T01:54:52Z | - |
dc.date.issued | 2007-12-22 | - |
dc.identifier.citation | Radiology. 2008 ;246(1):71-80. | en |
dc.identifier.issn | 1527-1315 (Electronic) | - |
dc.identifier.issn | 0033-8419 (Print) | - |
dc.identifier.uri | http://radiology.rsna.org/content/246/1/71.full.pdf | - |
dc.identifier.uri | https://hdl.handle.net/10371/62411 | - |
dc.description.abstract | PURPOSE: To retrospectively evaluate the sensitivity and reproducibility of a computer-aided detection (CAD) system applied to serial digital mammograms obtained in women with breast cancer, with histologic analysis as the reference standard. MATERIALS AND METHODS: This study was institutional review board approved, and patient informed consent was waived. A commercially available CAD system was applied to initial and follow-up digital mammograms obtained in 93 women with breast cancer (mean age, 52 years; age range, 32-81 years). The mean interval between mammographic examinations was 23 days (range, 7-58 days). There were 119 visible lesion components (70 masses, 49 microcalcifications). Sensitivity, false-positive mark rate, and reproducibility of the CAD system were evaluated for both sets of mammograms with the t test. RESULTS: Sensitivities of the CAD system at initial and follow-up digital mammography were 91% and 89%, respectively, for detection of masses. Sensitivity of the CAD system for detection of microcalcifications was 100% at both initial and follow-up digital mammography. Overall false-positive mark rates were 0.29 per image and 0.27 per image at initial and follow-up digital mammography, respectively. When craniocaudal and mediolateral oblique views were considered separately, sensitivities were 76% and 75%, respectively, for masses and 96% and 92%, respectively, for microcalcifications. The reproducibility of CAD marks was 80% for true-positive masses, 92% for true-positive microcalcifications, 9% for false-positive masses, and 8% for false-positive microcalcifications (P < .001). CONCLUSION: The sensitivity of the CAD system was consistently high for detection of breast cancer on initial and short-term follow-up digital mammograms. Reproducibility was significantly higher for true-positive CAD marks than for false-positive CAD marks. SUPPLEMENTAL MATERIAL: http://radiology.rsnajnls.org/cgi/content/full/246/1/71/DC1. | en |
dc.language.iso | en | en |
dc.publisher | Radiological Society of North America (RSNA) | en |
dc.subject | Adult | en |
dc.subject | Aged | en |
dc.subject | Aged, 80 and over | en |
dc.subject | Breast Neoplasms/pathology/*radiography | en |
dc.subject | Female | en |
dc.subject | Humans | en |
dc.subject | Mammography/*methods | en |
dc.subject | Middle Aged | en |
dc.subject | Retrospective Studies | en |
dc.subject | Sensitivity and Specificity | en |
dc.subject | Diagnosis, Computer-Assisted | - |
dc.subject | Radiographic Image Enhancement | - |
dc.title | Computer-aided detection in full-field digital mammography: sensitivity and reproducibility in serial examinations | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 김승자 | - |
dc.contributor.AlternativeAuthor | 문우경 | - |
dc.contributor.AlternativeAuthor | 조나리야 | - |
dc.contributor.AlternativeAuthor | 차주희 | - |
dc.contributor.AlternativeAuthor | 김선미 | - |
dc.contributor.AlternativeAuthor | 임정기 | - |
dc.identifier.doi | 10.1148/radiol.2461062072 | - |
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