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Absorption of D-Glucose and L-Leucine by Isolated Bowel Segments in Rats

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Authors
Lee, Seong-Cheol; Kim, Woo-Ki
Issue Date
1992-12
Publisher
Seoul National University College of Medicine
Citation
Seoul J Med, Vol.33 No.4, pp. 269-273
Keywords
Isolated bowel segmentAbsorptionD-GlucoseL-Leucine
Abstract
For clinical application of the technique for creation of an isolated bowel
segment(IBS) for lengthening the intestine, the absorptive function of the IBS was
measured in rats. An IBS is a segment of the intestine which is devoid of its mesentery
and nourished solely by the collaterals from the abdominal wall. The technique for creation
of the IBS has been established, but its absorptive function has yet to be
explored. Absorptive clearance of D-glucose and L-leucine was compared between the
control loop and the IBS. Water flux, capacity and the intraluminal pressure of the
bowel segment were also measured, using the single-perfusion technique. This study
revealed that the IBS maintained substantial absorptive function and that the loss of
external innervation might have influenced water flux in the IBS.
ISSN
0582-6802
Language
English
URI
http://hdl.handle.net/10371/6251
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 33 No.4 (1992)
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