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Nonpalpable breast masses: evaluation by US elastography

Cited 112 time in Web of Science Cited 118 time in Scopus
Authors
Cho, Nariya; Moon, Woo Kyung; Park, Jeong Seon; Cha, Joo Hee; Jang, Mijung; Seong, Min Hyun
Issue Date
2008-04-04
Publisher
Korean Radiological Society
Citation
Korean J Radiol 2008;9(2):111-118
Keywords
Biopsy, Fine-NeedleBreast/pathology/*ultrastructureBreast Neoplasms/*ultrasonography*Elasticity Imaging TechniquesROC CurveSensitivity and SpecificityUltrasonography, Interventional
Abstract
OBJECTIVE: To compare the diagnostic performances of conventional ultrasound (US) and US elastography for the differentiation of nonpalpable breast masses, and to evaluate whether elastography is helpful at reducing the number of benign biopsies, using histological analysis as a reference standard. MATERIALS AND METHODS: Conventional US and real-time elastographic images were obtained for 100 women who had been scheduled for a US-guided core biopsy of 100 nonpalpable breast masses (83 benign, 17 malignant). Two experienced radiologists unaware of the biopsy and clinical findings analyzed conventional US and elastographic images by consensus, and classified lesions based on degree of suspicion regarding the probability of malignancy. Results were evaluated by receiver operating characteristic curve analysis. In addition, the authors investigated whether a subset of lesions was categorized as suspicious by conventional US, but as benign by elastography. RESULTS: Areas under the ROC curves (Az values) were 0.901 for conventional US and 0.916 for elastography (p = 0.808). For BI-RADS category 4a lesions, 44% (22 of 50) had an elasticity score of 1 and all were found to be benign. CONCLUSION: Elastography was found to have a diagnostic performance comparable to that of conventional US for the differentiation of nonpalpable breast masses. The authors conclude that BI-RADS category 4a lesions with an elasticity score of 1 probably do not require biopsy.
ISSN
1229-6929 (Print)
Language
English
URI
http://hdl.handle.net/10371/62740
DOI
https://doi.org/10.3348/kjr.2008.9.2.111
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College of Medicine/School of Medicine (의과대학/대학원)Radiology (영상의학전공)Journal Papers (저널논문_영상의학전공)
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