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Facial wrinkles as a predictor of decreased renal function

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dc.contributor.authorPark, Byung-Hyun-
dc.contributor.authorLee, Sik-
dc.contributor.authorPark, Jin-Woo-
dc.contributor.authorKim, Kyung-Ah-
dc.contributor.authorKim, Han-Uk-
dc.contributor.authorLee, Ju-Hyung-
dc.contributor.authorKoh, Dai-Ha-
dc.contributor.authorYoum, Jung-Ho-
dc.contributor.authorYoo, Nina-
dc.contributor.authorPark, Sue-Kyung-
dc.contributor.authorKwon, Keun-Sang-
dc.date.accessioned2010-04-13-
dc.date.available2010-04-13-
dc.date.issued2008-09-06-
dc.identifier.citationNephrology (Carlton). 2008 ;13(6):522-7.en
dc.identifier.issn1440-1797 (Electronic)-
dc.identifier.urihttps://hdl.handle.net/10371/63016-
dc.description.abstractAIMS: Oxidative stress generated either by exogenous or endogenous sources can lead to progressive organ damage and skin ageing over a long period of time. Moreover, some dermatological signs are independent of chronological ageing, and may reflect the long-term redox state of internal organs. Therefore, we hypothesized that there might be an association between facial wrinkles and decreased renal function, an oxidative stress-related disease. METHODS: A cross-sectional study was carried out in a Korean population of 264 adults aged 30 years and older. Facial wrinkle scores in the crow's-foot area were estimated using a standardized form of visual assessment. As an index of renal function, we determined estimated glomerular filtration rate (eGFR). Lipid hydroperoxide (LPO) assay was performed to measure the levels of oxidative stress. RESULTS: After adjusting for possible confounders, lower eGFRs and higher LPO levels were found in those with severe facial wrinkles. CONCLUSION: We conclude that severe facial wrinkles might be used as a predictive marker of decreased renal function, independently of age, gender and other established risk factors.en
dc.language.isoenen
dc.publisherWiley-Blackwellen
dc.subjectAdulten
dc.subjectAge Factorsen
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectCross-Sectional Studiesen
dc.subjectFaceen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectGlomerular Filtration Rate-
dc.subjectSkin Aging-
dc.titleFacial wrinkles as a predictor of decreased renal functionen
dc.typeArticleen
dc.contributor.AlternativeAuthor박병현-
dc.contributor.AlternativeAuthor이식-
dc.contributor.AlternativeAuthor박진우-
dc.contributor.AlternativeAuthor김경아-
dc.contributor.AlternativeAuthor김한억-
dc.contributor.AlternativeAuthor이주형-
dc.contributor.AlternativeAuthor고대하-
dc.contributor.AlternativeAuthor염정호-
dc.contributor.AlternativeAuthor유니나-
dc.contributor.AlternativeAuthor박수경-
dc.contributor.AlternativeAuthor권근상-
dc.identifier.doi10.1111/j.1440-1797.2008.00977.x-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Preventive Medicine (예방의학전공)Journal Papers (저널논문_예방의학전공)
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