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Nasal cavity paraganglioma with malignant transformation: a case report

Cited 8 time in Web of Science Cited 8 time in Scopus
Authors
Jin, Hong-Ryul; Lee, Ok-Jun; Ahn, Youngjin
Issue Date
2007-09-25
Publisher
Elsevier
Citation
Auris Nasus Larynx. 2008 ;35(1):137-9.
Keywords
AdultCell Transformation, Neoplastic/*pathologyDiagnosis, DifferentialEndoscopyEpistaxis/etiologyFemaleHumansNasal Cavity/*pathology/surgeryNeuroectodermal Tumors, Primitive/pathology/surgeryNose Neoplasms/*pathology/surgeryParaganglioma/*pathology/surgeryS100 Proteins/analysisSarcoma, Ewing's/pathology/surgeryTumor Markers, Biological/analysisTurbinates/*pathology/surgery
Abstract
BACKGROUND: In this report, we describe a young woman with a nasal cavity paraganglioma with malignant transformation. METHODS AND RESULTS: A 23-year-old woman presented with frequent right-sided epistaxis. Physical examination revealed a pedunculated mass originating from the right superior turbinate and filling the posterior nasal cavity. The endoscopically removed mass was composed of a reddish anterior portion and a white, flesh-looking posterior portion, the latter comprising the majority of the tumor. Histologically, the anterior portion showed a paraganglioma and the posterior portion showed a separate malignant lesion simulating Ewing's sarcoma/PNET. She underwent wide endoscopic excision including the site of tumor origin and has been followed up for 3 years without any evidence of disease recurrence. CONCLUSION: This is a rare case of nasal cavity paraganglioma that had transformed into a malignant tumor.
ISSN
0385-8146 (Print)
Language
English
URI
https://hdl.handle.net/10371/63052
DOI
https://doi.org/10.1016/j.anl.2007.05.009
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College of Medicine/School of Medicine (의과대학/대학원)Otorhinolaryngology (이비인후과학전공)Journal Papers (저널논문_이비인후과학전공)
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