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Elastic fiber staining and cytokeratin 15 expression pattern in trichoepithelioma and basal cell carcinoma

Cited 10 time in Web of Science Cited 15 time in Scopus
Issue Date
2008-09-16
Publisher
Wiley-Blackwell
Citation
J Dermatol. 2008 ;35(8):499-502.
Keywords
Biological Markers/analysisCarcinoma, Basal Cell/*diagnosis/metabolism/pathologyDiagnosis, DifferentialElastic Tissue/*pathologyHistocytochemistryHumansImmunohistochemistryKeratin-15/*analysisNeoplasms, Basal Cell/*diagnosis/metabolism/pathologySkin Neoplasms/*diagnosis/metabolism/pathologyStaining and Labeling
Abstract
Trichoepithelioma (TE) is a benign neoplasm of the skin that resembles basal cell carcinoma (BCC) in its clinical and histological features. In this study, we evaluate the usefulness of elastic fiber staining and cytokeratin 15 expression pattern in terms of distinguishing TE from BCC. Eleven TE and 17 BCC were examined histochemically and immunohistochemically. It was found that BCC contain more elastic fiber than TE, and that more TE show peripheral localization than BCC in cytokeratin 15 expression patterns. The present study shows that elastic fiber staining and cytokeratin 15 expression pattern may aid the differentiation of TE from BCC.
ISSN
0385-2407 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18789069

https://hdl.handle.net/10371/63626
DOI
https://doi.org/10.1111/j.1346-8138.2008.00510.x
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College of Medicine/School of Medicine (의과대학/대학원)Dermatology (피부과학전공)Journal Papers (저널논문_피부과학전공)
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