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Clinical Study of Prophylactic Antibiotics to Determine the Optimum Duration of Administration
예방적 항생제의 적정 투여기간 결정을 위한 임상적 연구

DC Field Value Language
dc.contributor.authorKim, Jin-Pok-
dc.contributor.authorKim, Sun-Whe-
dc.date.accessioned2009-08-07-
dc.date.available2009-08-07-
dc.date.issued1985-09-
dc.identifier.citationSeoul J Med, Vol.26 No.2, pp. 221-227-
dc.identifier.issn0582-6802-
dc.identifier.urihttps://hdl.handle.net/10371/6397-
dc.description.abstractTo confirm the benefits of short term perioperative chemoprophylaxis a
prospective randomized comparative study was performed. The patients admitted for elective
gastroduodenal or biliary tract surgery had been enrolled. The patients were given two different
antibiotic regimens; cefazolin (I) or combination of penicillin and gentamicin (II), for three
different periods starting preoperatively; 1 day (group A), 3 days (group B) and 5 to 7 days
(group C). The each group of patients was similar in terms of age, sex, weight, duration of
operation, preoperative hospital days and distribution of disease and operation. The rate of
infection was 5.1% (5/99) in group A, 7.7% (8/104) in group Band 6.9% (7/101) in group C.
No significant difference was found between cefazolin alone (5.8%) and penicillin plus gentamicin
(7.3%) in the rate of infection. This result suggests that there is no benefit from
continuing antibiotic administration beyond the day of operation in preventing infectious complication
after clean contaminated operation.
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dc.language.isoen-
dc.publisherSeoul National University College of Medicine-
dc.subjectAntibiotic prophylaxis-
dc.subjectDecisive period-
dc.subjectClean contaminated surgery-
dc.titleClinical Study of Prophylactic Antibiotics to Determine the Optimum Duration of Administration-
dc.title.alternative예방적 항생제의 적정 투여기간 결정을 위한 임상적 연구-
dc.typeSNU Journal-
dc.contributor.AlternativeAuthor김진복-
dc.contributor.AlternativeAuthor김선회-
dc.citation.journaltitle서울 의대 잡지-
dc.citation.journaltitle서울 의대 학술지-
dc.citation.journaltitleSeoul Journal of Medicine-
dc.citation.endpage227-
dc.citation.number2-
dc.citation.pages221-227-
dc.citation.startpage221-
dc.citation.volume26-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 26 No.2 (1985)
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