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Animal scale-up and first-pass effects, pharmacokinetics in various rat disease models, and drug interaction with DDB of liquiritigenin in rats : 염증성 간질환 치료후보제 liquritigenin의 animal scale-up과 초회통과 효과, 각종 질병 모델에서의 pharmacokinetics, 및 DDB와의 상호작용에 관한 연구
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- Authors
- Advisor
- 이명걸
- Issue Date
- 2010
- Publisher
- 서울대학교 대학원
- Keywords
- liquiritigenin ; liquiritigenin ; M1 and M2 ; M1 and M2 ; pharmacokinetics ; pharmacokinetics ; animal-scale up ; animal scale-up ; 초회통과효과 ; first-pass effects ; 질병모델 (급성간염 ; pharmacokinetic changes in acute hepatitis induced by GalN ; 당뇨 ; LPS or CCl4 ; 급성신부전)에서 pharmacokinetic 변화 ; DMIS ; DDB와 약물 상호작용 ; and U-ARF rats ; UGT ; drug interaction with DDB ; UDPGA ; UGT ; UDPGA
- Description
- Thesis(doctors) --서울대학교 대학원 :약학과(약물학전공),2010.2.
- Language
- English
- URI
- http://dcollection.snu.ac.kr:80/jsp/common/DcLoOrgPer.jsp?sItemId=000000032434
https://hdl.handle.net/10371/64111
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