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Effect of Corticosterone on the Serotonin Receptor Binding Properties in Rat Cerebral Cortex : Corticosterone이 흰쥐 대뇌피질 serotonin 수용체 결합성에 미치는 영향에 관한 연구
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Sung Woo | - |
dc.contributor.author | Suh, Yoo Hun | - |
dc.contributor.author | Woo, Jong Inn | - |
dc.contributor.author | Park, Chan-Woong | - |
dc.date.accessioned | 2009-08-07T09:01:23Z | - |
dc.date.available | 2009-08-07T09:01:23Z | - |
dc.date.issued | 1987-12 | - |
dc.identifier.citation | Seoul J Med, Vol.28 No.4, pp. 303-309 | - |
dc.identifier.issn | 0582-6802 | - |
dc.identifier.uri | https://hdl.handle.net/10371/6553 | - |
dc.description.abstract | A possible role of brain serotonin in the regulation of HPA axis activity including
feed-back sensitivity has been studied by many investigators. The present study was undertaken to check the serotonin binding to rat cerebral cortex membrane before and after corticosterone replacement in adrenalectomized rats. Both the affinity and the number of serotonin binding sites were significantly increased following corticosterone replacement, compared to those of adrenalectomized control. In conclusion, the present study strongly suggests that cerebral cortical serotonin receptor sensitivity might be changed by repeated treatment with corticosterone and may support the assumption of serotoninergic regulation in feed-back activity of HPA axis. | - |
dc.language.iso | en | - |
dc.publisher | Seoul National University College of Medicine | - |
dc.subject | Serotonin receptor | - |
dc.subject | Corticosterone | - |
dc.subject | Rat brain | - |
dc.subject | Adrenalectomy | - |
dc.title | Effect of Corticosterone on the Serotonin Receptor Binding Properties in Rat Cerebral Cortex | - |
dc.title.alternative | Corticosterone이 흰쥐 대뇌피질 serotonin 수용체 결합성에 미치는 영향에 관한 연구 | - |
dc.type | SNU Journal | - |
dc.contributor.AlternativeAuthor | 박성우 | - |
dc.contributor.AlternativeAuthor | 서유헌 | - |
dc.contributor.AlternativeAuthor | 우종인 | - |
dc.contributor.AlternativeAuthor | 박찬웅 | - |
dc.citation.journaltitle | 서울 의대 잡지 | - |
dc.citation.journaltitle | 서울 의대 학술지 | - |
dc.citation.journaltitle | Seoul Journal of Medicine | - |
dc.citation.endpage | 309 | - |
dc.citation.number | 4 | - |
dc.citation.pages | 303-309 | - |
dc.citation.startpage | 303 | - |
dc.citation.volume | 28 | - |
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