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Oleanolic Acid 유도체의 소염작용에 관한 연구 : Study of anti-inflammatory action of the oIeanoIic acid derivatives.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김현우 | - |
dc.date.accessioned | 2009-08-07T11:11:07Z | - |
dc.date.available | 2009-08-07T11:11:07Z | - |
dc.date.issued | 1971-06 | - |
dc.identifier.citation | Seoul J Med, Vol.12 No.2, pp. 109-115 | - |
dc.identifier.issn | 0582-6802 | - |
dc.identifier.uri | https://hdl.handle.net/10371/6579 | - |
dc.description.abstract | Anti-inflammatory effects of the oleanolic acid
derivatives, glycyrrhizine, and hydrocortisone are observed on formalin-induced arthritis in rats. One of the oleanolic acid derivatives, 2-acetoxyll- keto-612 , 13 30-acetoxymethylketo oleanolic acid as well as hydrocortisone has significant action of anti-inflammation upon formalin-induced arthritis in rats, while 2-acetoxy-L11z, 13 28-oxymethylketo oeanolic acid, acetyl oleanolic acid and glycyrrhizine show dou btful results. Serum glutamic oxalacetic transaminase (S-GOT) and serum glutamic pyruvic transaminase (S-GPT) activities increase with 'inflammation, and they are inhibited by anti-inflammatory drugs. Adenosine triphosphatase (ATP-ase) activities in brain and liver tissues do not give any significance to formalin-induced arthritis in rats, but it is increased definitly by anti-inflammatory drugs. There seems to be no relationship between anti-inflammatory effects of anti-inflammatory drugs and activities of S-GOT and S-GPT as well as that of ATP-ase. | - |
dc.language.iso | ko | - |
dc.publisher | 서울대학교 의과대학 | - |
dc.title | Oleanolic Acid 유도체의 소염작용에 관한 연구 | - |
dc.title.alternative | Study of anti-inflammatory action of the oIeanoIic acid derivatives. | - |
dc.type | SNU Journal | - |
dc.contributor.AlternativeAuthor | Kim, Hyun Woo | - |
dc.citation.journaltitle | 서울 의대 잡지 | - |
dc.citation.journaltitle | 서울 의대 학술지 | - |
dc.citation.journaltitle | Seoul Journal of Medicine | - |
dc.citation.endpage | 115 | - |
dc.citation.number | 2 | - |
dc.citation.pages | 109-115 | - |
dc.citation.startpage | 109 | - |
dc.citation.volume | 12 | - |
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